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Onion-Pumpkin Extract

Phase 2

Blood Pressure | Unknown | Other |Medicus Pharma Ltd.|Last Updated: Feb 2, 2015

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment10
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT02353104The Effects of the Onion-Pumpkin Extract on Blood PressurePHASE2 COMPLETED 10Nov 1, 2013Aug 1, 2014Feb 2, 2015 -
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Study Endpoints
Primary Endpoints
Systolic Blood Pressure
12 weeks

Change in Individual SBP Values

Systolic Blood Pressure (Change in Mean SBP Values)
12 weeks

Change in Mean SBP Values

Diastolic Blood Pressure (Change in Individual DBP Values)
12 weeks

Change in Individual DBP Values

Diastolic Blood Pressure (Change in Mean DBP Values)
12 weeks

Change in Mean DBP Values

Secondary Endpoints
Change in complete blood cell count (CBC)
12 weeks
Change in Comprehensive Metabolic Panel (CMP)
12 weeks
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Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeSUPPORTIVE_CARE
Treatment Arms
ArmTypeDescription
Onion-Pumpkin ExtractEXPERIMENTALTake two capsules, twice daily before breakfast and dinner
Interventions
NameTypeDescription
Onion-Pumpkin ExtractDIETARY_SUPPLEMENT -
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersYes

Inclusion Criteria: * BMI ≥ 25 and ≤ 35 kg/m2 * Blood pressure: * SBP: 140-160 mmHg * DBP: 80-90 mmHg * Judged by the Investigator to be in general good health on the basis of medical history * Females of child bearing potential must agree to use appropriate birth control methods during the en...

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