Recent Updates
Recently added Catalysts

WP1220

Phase 1

Cutaneous T-Cell Lymphoma/Mycosis Fungoides | Small molecule | Dermatology |Moleculin Biotech, Inc.|Last Updated: Jan 11, 2021

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment5

FDA Designations

No designations recorded

Clinical trial landscape

WP1220 · 1 trial · 1 indication

Phase 1 1
NCT04702503Study of WP1220 for the Treatment of Adult Subjects With Cutaneous T-Cell Lymphoma (CTCL)Cutaneous T-Cell Lymphoma/Mycosis Fungoides
COMPLETED5 Analytics
PHASE1COMPLETED
Study of WP1220 for the Treatment of Adult Subjects With Cutaneous T-Cell Lymphoma (CTCL)
Cutaneous T-Cell Lymphoma/Mycosis FungoidesUnlock trial analytics

Study Endpoints

Primary Endpoints

Evaluation of the safety profile of WP1220 applied topically (adverse events)
12 weeks (3 28-day cycles)

Safety will be evaluated by reported adverse events

Secondary Endpoints

Evaluation of WP1220 applied topically to index lesions via standard measurement scale
12 weeks
Unlock Study Endpoints

Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
10% WP1220 ointmentEXPERIMENTAL10% WP1220 ointment topically applied 2x day for 84 days

Interventions

NameTypeDescription
WP1220DRUGTopical administration 2x daily for 84 consecutive days
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: 1. Age ≥ 18 years at the time of signing informed consent. 2. Clinical diagnosis of MF. 3. Stage IA, IB, IIA, IIB, or II MF: T1-T4 with measurable lesions 4. Previously treatment with at least one standard therapy used to treat Stage IA, IB, IIA, IIB, or III MF. 5. Measurable sk...

Countries:Poland
Unlock Eligibility Criteria

Frequently asked questions about WP1220

What is WP1220 used for?

WP1220 is an investigational small molecule being studied for the treatment of cutaneous T-cell lymphoma and mycosis fungoides, a type of skin lymphoma. It is intended for adult patients with these conditions. The drug is in early clinical development and is not yet approved for commercial use.

Who makes WP1220?

WP1220 is being developed by Moleculin Biotech, Inc., a biopharmaceutical company. The company's stock is traded under the ticker symbol MBRX. Moleculin is conducting clinical research to evaluate the safety and efficacy of WP1220 in patients with cutaneous T-cell lymphoma.

What phase is WP1220 in?

WP1220 is in Phase 1 clinical development. It has completed a Phase 1 trial, which was an uncontrolled, open-label study. The drug is still investigational and has not received regulatory approval. Further clinical studies would be needed to assess its safety and effectiveness in larger patient populations.

What clinical trials is WP1220 in?

WP1220 has been studied in one clinical trial with the identifier NCT04702503. This was a Phase 1 study titled 'Study of WP1220 for the Treatment of Adult Subjects With Cutaneous T-Cell Lymphoma (CTCL)'. The trial was completed and enrolled 5 participants in Poland.

Is WP1220 FDA approved?

WP1220 is not FDA approved. It is an investigational drug that has completed a Phase 1 clinical trial. The drug is still in clinical development and has not been evaluated in later-stage trials. Regulatory approval would require additional studies demonstrating safety and efficacy.