Recent Updates
Recently added Catalysts

WP1220

Phase 1

Cutaneous T-Cell Lymphoma/Mycosis Fungoides | Small molecule | Oncology |Moleculin Biotech, Inc.|Last Updated: Jan 11, 2021

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment5
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT04702503Study of WP1220 for the Treatment of Adult Subjects With Cutaneous T-Cell Lymphoma (CTCL)PHASE1 COMPLETED 5Mar 8, 2019Nov 15, 2020Jan 11, 20211 Poland
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Evaluation of the safety profile of WP1220 applied topically (adverse events)
12 weeks (3 28-day cycles)

Safety will be evaluated by reported adverse events

Secondary Endpoints
Evaluation of WP1220 applied topically to index lesions via standard measurement scale
12 weeks
Unlock Study Endpoints
Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
10% WP1220 ointmentEXPERIMENTAL10% WP1220 ointment topically applied 2x day for 84 days
Interventions
NameTypeDescription
WP1220DRUGTopical administration 2x daily for 84 consecutive days
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: 1. Age ≥ 18 years at the time of signing informed consent. 2. Clinical diagnosis of MF. 3. Stage IA, IB, IIA, IIB, or II MF: T1-T4 with measurable lesions 4. Previously treatment with at least one standard therapy used to treat Stage IA, IB, IIA, IIB, or III MF. 5. Measurable sk...

Countries:Poland
Unlock Eligibility Criteria