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VDMN-21 Patch Low Dose

Phase 2

Verruca Vulgaris | Small molecule | Infectious Disease |Veradermics, Incorporated|Last Updated: May 8, 2025

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDDMC
Total Trials1
Total Enrollment153

FDA Designations

No designations recorded

Clinical trial landscape

VDMN-21 Patch Low Dose · 1 trial · 3 indications

Phase 2 1
NCT05799157Safety and Efficacy of VDMN-21 Patch in Subjects With Common WartsVerruca Vulgaris
COMPLETED153 Analytics
PHASE2COMPLETED
Safety and Efficacy of VDMN-21 Patch in Subjects With Common Warts
Verruca VulgarisUnlock trial analytics

Study Endpoints

Primary Endpoints

Proportion of subjects with complete clinical resolution of the Target Lesion at end of treatment period
Baseline up to Day 134

Complete clinical resolution is defined as the target lesion with area = 0.

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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Treatment Group A (Low Dose)EXPERIMENTALLow does patch will be applied adjacent to the target wart and remain in place for 5 minutes then removed. There may be up to 6 treatments (approximately 1 per month).
Treatment Group B (High Dose)EXPERIMENTALHigh does patch will be applied adjacent to the target wart and remain in place for 5 minutes then removed. There may be up to 6 treatments (approximately 1 per month).
Treatment Group C (Vehicle)PLACEBO_COMPARATORVehicle patch will be applied adjacent to the target wart and remain in place for 5 minutes then removed. There may be up to 6 treatments (approximately 1 per month).

Interventions

NameTypeDescription
VDMN-21 Patch Low DoseDRUGMicroneedle patch containing 125 mcg of active drug
VDMN-21 Patch High DoseDRUGMicroneedle patch containing 250 mcg of active drug
Vehicle PatchDRUGPlacebo microneedle patch containing no active drug (i.e., placebo)
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Eligibility Criteria

Age Range9 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites16

Inclusion Criteria: * Subject is a male or non-pregnant female, 9 to 65 years of age. * Subject has provided written informed consent/assent. * Females must be post-menopausal, surgically sterile, or use an effective method of birth control. Women of childbearing potential (WOCBP) must have a negat...

Countries:United States
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Frequently asked questions about VDMN-21 Patch Low Dose

What is VDMN-21 Patch Low Dose used for?

VDMN-21 Patch Low Dose is an investigational small molecule patch being developed for the treatment of Verruca Vulgaris, commonly known as common warts. It is designed for topical application to treat this infectious disease condition. The drug is currently in clinical development and has not been approved by regulatory authorities.

What does VDMN-21 Patch Low Dose target?

The specific molecular target of VDMN-21 Patch Low Dose has not been disclosed in available information. The drug is classified as a small molecule modality and is being investigated for its safety and efficacy in treating Verruca Vulgaris, or common warts, through topical application as a patch.

Who makes VDMN-21 Patch Low Dose?

VDMN-21 Patch Low Dose is being developed by Veradermics, Incorporated, a biopharmaceutical company. The company is conducting clinical trials to evaluate the safety and efficacy of this investigational patch for the treatment of common warts.

What phase is VDMN-21 Patch Low Dose in?

VDMN-21 Patch Low Dose is in Phase 2 clinical development. It is an investigational drug that has not been approved by the FDA or any other regulatory agency. The drug is being studied for its safety and efficacy in treating Verruca Vulgaris, or common warts.

What clinical trials is VDMN-21 Patch Low Dose in?

VDMN-21 Patch Low Dose has been studied in one completed Phase 2 clinical trial, identified as NCT05799157. This randomized, double-blind, placebo-controlled trial enrolled 153 participants in the United States to evaluate the safety and efficacy of the patch in subjects with common warts.

Is VDMN-21 Patch Low Dose the same as VDMN-21?

VDMN-21 Patch Low Dose is a specific formulation of the investigational drug VDMN-21, developed by Veradermics, Incorporated. The 'Low Dose' designation indicates a particular strength of the patch being evaluated in clinical trials for the treatment of common warts.