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Latigo Biotherapeutics, Inc.

LTGOFDA catalysts, PDUFA dates & pipeline intelligence
$13.95
▼ -1.92 · -12.36%

Financials

Last updated
Revenue
R&D Expenses
Operating CF
Total Assets
Total Liabilities
Equity
Shares Out.
D/E Ratio
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Quarterly Cash
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Volume
216.17 K
Value Traded
10.93 M
Short % Float
2.67%
Days to Cover
2.5
-8.58%Week
-16.42%1 Month
-23.56%3 Month

Cash Data

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  • Burn Trend
  • Dilution Risk
  • SEC Filing

Key Stats

Market Cap
924.88 M
EPS (TTM)
-
P/E Ratio
-
Ent. Value
904.87 M
Total Shares
66.30 M
Float Shares
29.47 M
Insiders
55.55%
Institutions
14.78%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 3 topline data readout
onzotrigine (LTG-001)
Moderate-to-severe acute pain after bunionectomy surgery
Phase 3Small MoleculesNervous System
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

LTGO Catalyst Timeline

Dated clinical, regulatory and corporate events for Latigo Biotherapeutics, Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Latigo Biotherapeutics, Inc.

11Total events
4Upcoming
2Tier-1 (high impact)
2026 to 2029Coverage

Upcoming catalysts 2

T1Topline Readout
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onzotrigine
T1Topline Readout
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LTG-321

Event history 6

▲PublicationonzotriginePresentation
NEJM published positive abdominoplasty trial results
moderate-to-severe acute painsource ↗
▲Trial InitiationLTG-321Trial
Initiated Phase 2 trial of LTG-321
osteoarthritis of the kneesource ↗
▲Preclinical PoCLTG-418Preclinical
Completed 14-day non-GLP toxicology studies for LTG-418
acute and chronic painsource ↗
●Management ChangeCorporate
Appointed Naomi Lowy as SVP of global regulatory affairs
●Quarterly UpdateCorporate
Reported Q2 2026 financial results
●IpoCorporate
Completed upsized initial public offering
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How LTGO actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
-Example Drug Phase 3 data readout Phase 3
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

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Every scored asset with PTRS, rNPV, enrollment velocity and trial design quality.
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Clinical Trial Results

Readouts, endpoints and source filings for every LTGO program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
Example Drug Example indication for clinical evaluationPhase 32025-12-01The study met its primary endpoint demonstrating statistically significant improvement.Read MorePhase 3 Study Results AnnouncementRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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Monthly insider buys and sells against the stock price, with the insider sentiment reading.
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InsiderSideSharesPriceValueDate
Foresite Capital Management V, LLC10% OwnerBuy 140,000 2,008,024 held$18.00 08/10/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
No hedge fund reported a 13F position in LTGO for Q2 2026.
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Every 13F position with quarter over quarter share flow and average entry price.
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Shares held by hedge funds each quarter, and who bought or sold.

LTGO Institutional Ownership Trends

LTGO Short Interest

Shares sold short, counted twice a month.

2.67%
Short % of Float
of tradable shares sold short
785.9K
Shares Sold Short
-5.6% vs prior count
2.5 Moderate
Days to Cover
trading days of normal volume to buy every short share back
314.8K
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Live calls and puts by strike: last price, volume and open interest for every expiry.
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Calls vs Puts by Expiry

CallsPutsLog scale
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Competitive positioning

How LTGO ranks across every disease it competes in

Competitive Position is a premium feature
See how LTGO ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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LTGO News

-LTGO
Sep 3, 2026
LTGOGeneral

Latigo Biotherapeutics Reports Second Quarter 2026 Financial Results and Recent Business Highlights

Latigo Biotherapeutics reported strong financial results for Q2 2026, highlighted by a successful IPO that raised $397.4 million. The company published positive clinical trial results for its pain medication onzotrigine in the New England Journal of Medicine. Additionally, Latigo expanded its leadership team with the appointment of Dr. Naomi Lowy, enhancing its regulatory affairs capabilities.

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-LTGO
Aug 7, 2026
LTGOGeneral

Latigo Biotherapeutics Announces Pricing of Upsized $345.6 Million Initial Public Offering

Latigo Biotherapeutics has announced the pricing of its upsized initial public offering, offering 19.2 million shares at $18.00 each, aiming to raise $345.6 million. The shares will begin trading on Nasdaq under the ticker LTGO on August 7, 2026, with the offering expected to close on August 10, 2026. Goldman Sachs, Jefferies, Leerink Partners, and Guggenheim Securities are managing the offering.

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-LTGO
Jul 29, 2026
LTGOPhases

Latigo Biotherapeutics Announces New England Journal of Medicine Publication of Positive LTG-001 Abdominoplasty Clinical Trial Results in Moderate-to-Severe Acute Pain

Latigo Biotherapeutics has published positive results from its LTG-001 abdominoplasty clinical trial in the New England Journal of Medicine. The study demonstrated significant pain reduction and rapid analgesia in patients with moderate-to-severe postoperative pain. LTG-001, a selective Nav1.8 inhibitor, showed a greater analgesic effect than the opioid comparator, Vicodin, and has potential opioid-sparing benefits.

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-LTGO
Jul 8, 2026
LTGOGeneral

Latigo Biotherapeutics Appoints Todd Smith to its Board of Directors

Latigo Biotherapeutics has appointed Todd Smith to its board of directors. Smith, CEO of Corium, brings over three decades of experience in the biopharmaceutical industry, particularly in commercialization and product launches. His addition is seen as a strategic move to enhance Latigo's mission of developing innovative non-opioid pain therapies.

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-LTGO
Apr 8, 2026
LTGOGeneral

Latigo Biotherapeutics Appoints Sara M. Bonstein to its Board of Directors and as Audit Committee Chair

Latigo Biotherapeutics has appointed Sara M. Bonstein to its board of directors and as chair of the audit committee. Bonstein, currently CFO of Insmed, brings over 20 years of financial leadership experience in biotechnology. Her expertise is expected to support Latigo's growth and advancement of its non-opioid pain management pipeline.

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-LTGO
Mar 3, 2026
LTGOGeneral

Latigo Biotherapeutics Appoints Neha Krishnamohan as Chief Financial Officer and Chief Business Officer

Latigo Biotherapeutics has appointed Neha Krishnamohan as Chief Financial Officer and Chief Business Officer. With over 15 years of experience in healthcare investment banking and corporate finance, she is expected to play a crucial role in advancing Latigo's non-opioid pain pipeline. The company aims to address the opioid addiction crisis while improving pain management outcomes.

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-LTGO
Mar 17, 2025
LTGOGeneral

Latigo Biotherapeutics Closes $150 Million in Series B Financing to Advance Non-Opioid Pain Therapeutics

Latigo Biotherapeutics has successfully closed a $150 million Series B financing round to advance its non-opioid pain therapeutics, particularly focusing on its Na v 1.8 inhibitors. The funding, led by Blue Owl Capital, will support the development of Latigo's pipeline and its mission to provide safer pain management alternatives. The company recently reported positive Phase 1 results for its lead candidate, LTG-001.

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-LTGO
Mar 3, 2025
LTGOFDA Updates

Latigo Biotherapeutics Granted FDA Fast Track Designation for LTG-001, Potential Best-in-Class Nav1.8 Inhibitor for the Non-Opioid Treatment of Acute Pain

Latigo Biotherapeutics has received FDA Fast Track designation for LTG-001, an investigational Na v 1.8 inhibitor aimed at treating acute pain. This designation will expedite its development and regulatory review process. The Phase 1 trial results indicated a favorable safety profile and rapid absorption, suggesting potential for effective pain relief without opioid risks.

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-LTGO
Nov 19, 2024
LTGOGeneral

Latigo Biotherapeutics Appoints Industry Veteran Timothy P. Walbert as Board Chair

Latigo Biotherapeutics has appointed Timothy P. Walbert as the new chair of its board of directors. Walbert, who has extensive experience in the biopharmaceutical industry, previously led Horizon Therapeutics through its acquisition by Amgen. His appointment is expected to enhance Latigo's focus on developing non-opioid pain therapies.

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-LTGO
Oct 16, 2024
LTGOPhases

Latigo Biotherapeutics Doses First Participant in Phase 1 Clinical Trial of LTG-305 for Non-Opioid Treatment of Pain

Latigo Biotherapeutics has initiated a Phase 1 clinical trial for LTG-305, a non-opioid treatment for chronic pain. The trial will assess the safety, tolerability, and pharmacokinetics of LTG-305 in healthy volunteers. Results are expected in mid-2025, and the drug targets pain mechanisms with a focus on avoiding central nervous system side effects.

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About Latigo Biotherapeutics, Inc.

Thousand Oaks, CA latigobio.com
Headquarters1300 RANCHO CONEJO BLVD., SUITE 305, THOUSAND OAKS, CA
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