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LPCN 1144

Phase 2

NASH - Nonalcoholic Steatohepatitis | Small molecule | Infectious Disease |Lipocine Inc.|Last Updated: Jul 17, 2024

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment25
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT04685993A Study of the Safety and Tolerability of LPCN 1144 in Subjects Who Completed the LPCN 1144-18-002 TrialPHASE2 COMPLETED 25Nov 11, 2020Mar 1, 2022Jul 17, 202410 United States
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Study Endpoints
Primary Endpoints
Safety and Tolerability of LPCN 1144
Baseline to Week 36

Number of subjects presenting with a treatment-emergent adverse events

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Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Treatment AEXPERIMENTALLPCN 1144
Interventions
NameTypeDescription
LPCN 1144DRUGOral LPCN 1144, total daily dose of 450 mg testosterone undecanoate administered as BID (225 mg testosterone undecanoate per dose).
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Eligibility Criteria
Age Range18 Years — 80 Years
SexMALE
Healthy VolunteersNo
Study Sites10

Inclusion Criteria: 1. Subjects who have completed the 38 week study LPCN 1144-18-002 and wish to be treated with LPCN 1144 2. Subject must sign the Informed Consent Form to participate in the study Exclusion Criteria: 1. Has participated or is participating in any other clinical (investigational...

Countries:United States
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