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LPCN 1144

Phase 2

NASH - Nonalcoholic Steatohepatitis | Small molecule | Metabolic |Lipocine Inc.|Last Updated: Jul 17, 2024

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDDMC
Total Trials1
Total Enrollment25

FDA Designations

No designations recorded

Clinical trial landscape

LPCN 1144 · 1 trial · 1 indication

Phase 2 1
NCT04685993A Study of the Safety and Tolerability of LPCN 1144 in Subjects Who Completed the LPCN 1144-18-002 TrialNASH - Nonalcoholic Steatohepatitis
COMPLETED25 Analytics
PHASE2COMPLETED
A Study of the Safety and Tolerability of LPCN 1144 in Subjects Who Completed the LPCN 1144-18-002 Trial
NASH - Nonalcoholic SteatohepatitisUnlock trial analytics

Study Endpoints

Primary Endpoints

Safety and Tolerability of LPCN 1144
Baseline to Week 36

Number of subjects presenting with a treatment-emergent adverse events

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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Treatment AEXPERIMENTALLPCN 1144

Interventions

NameTypeDescription
LPCN 1144DRUGOral LPCN 1144, total daily dose of 450 mg testosterone undecanoate administered as BID (225 mg testosterone undecanoate per dose).
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Eligibility Criteria

Age Range18 Years to 80 Years
SexMALE
Healthy VolunteersNo
Study Sites10

Inclusion Criteria: 1. Subjects who have completed the 38 week study LPCN 1144-18-002 and wish to be treated with LPCN 1144 2. Subject must sign the Informed Consent Form to participate in the study Exclusion Criteria: 1. Has participated or is participating in any other clinical (investigational...

Countries:United States
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Frequently asked questions about LPCN 1144

What is LPCN 1144 used for?

LPCN 1144 is an investigational small molecule being developed for the treatment of nonalcoholic steatohepatitis (NASH), a metabolic liver condition. It is currently in Phase 2 clinical development and has not been approved by the FDA. The drug is intended for adult male patients with NASH.

Who makes LPCN 1144?

LPCN 1144 is being developed by Lipocine Inc., a biopharmaceutical company traded on the NASDAQ under the ticker symbol LPCN. The company is conducting clinical trials to evaluate the safety and tolerability of this investigational drug for the treatment of nonalcoholic steatohepatitis (NASH).

What phase is LPCN 1144 in?

LPCN 1144 is in Phase 2 clinical development. It is an investigational drug, meaning it has not been approved by the FDA for any use. The drug is being studied for the treatment of nonalcoholic steatohepatitis (NASH) in adult male patients.

What clinical trials is LPCN 1144 in?

LPCN 1144 has one completed Phase 2 clinical trial registered as NCT04685993. This study evaluated the safety and tolerability of LPCN 1144 in 25 adult male subjects with nonalcoholic steatohepatitis (NASH) in the United States. The trial was uncontrolled and not randomized or double-blinded.

How does LPCN 1144 work?

The specific molecular target and mechanism of action for LPCN 1144 have not been disclosed in available clinical trial information. The drug is classified as a small molecule and is being investigated for its potential therapeutic effect in nonalcoholic steatohepatitis (NASH), a metabolic liver disease.