Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Vagus Nerve Stimulation · 1 trial · 1 indication
Left ventricular end-systolic volume (LVESV) and ejection fraction (EF)
Incidence of procedure and device-related complications
| Arm | Type | Description |
|---|---|---|
| Left Sided Stimulation | EXPERIMENTAL | Left cervical Vagus Nerve Stimulation (VNS) |
| Right Sided Stimulation | EXPERIMENTAL | Right Cervical Vagus Nerve Stimulation (VNS) |
| Name | Type | Description |
|---|---|---|
| Vagus Nerve Stimulation (VNS) | DEVICE | Electrical Stimulation of the Vagus Nerve |
Inclusion Criteria: * Patients with symptomatic heart failure, New York Heart Association (NYHA) class II/III with reduced EF and dilated hearts
Vagus Nerve Stimulation is an investigational therapy being studied for the treatment of Congestive Heart Failure. It involves stimulating the vagus nerve to potentially enhance myocardial function in patients with this condition. The therapy is currently in Phase 1 clinical development and has not yet been approved by regulatory authorities.
Vagus Nerve Stimulation is being developed by LivaNova PLC, a company traded on the stock exchange under the ticker symbol LIVN. LivaNova is conducting clinical research to evaluate this therapy for the treatment of Congestive Heart Failure.
Vagus Nerve Stimulation is in Phase 1 clinical development for the treatment of Congestive Heart Failure. It is an investigational therapy, meaning it has not yet received regulatory approval and is still being evaluated in clinical trials to assess its safety and potential efficacy.
Vagus Nerve Stimulation has been studied in a completed clinical trial with the identifier NCT01823887, titled 'Autonomic Neural Regulation Therapy to Enhance Myocardial Function in Heart Failure (ANTHEM-HF) Study.' This Phase 1 trial enrolled 60 participants with Congestive Heart Failure and was conducted in India.
Vagus Nerve Stimulation is not the same as ANTHEM-HF. ANTHEM-HF is the name of a specific clinical trial, formally known as the 'Autonomic Neural Regulation Therapy to Enhance Myocardial Function in Heart Failure Study,' which evaluates Vagus Nerve Stimulation as an investigational treatment for Congestive Heart Failure.