Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Clomiphene · 1 trial · 1 indication
15 item self reported erectile function. Each item is scored 0-5 with 0=negative response and 5 = positive response with totals of 0-75
15 item self reported erectile function over the past 8 weeks. Each item is scored 0-5 with 0=negative response and 5 = positive response with totals of 0-75
15 item self reported erectile function over the past 8 weeks. Each item is scored 0-5 with 0=negative response and 5 = positive response with totals of 0-75
15 item self reported erectile function over the past 8 weeks. Each item is scored 0-5 with 0=negative response and 5 = positive response with totals of 0-75
| Arm | Type | Description |
|---|---|---|
| anastrazole-clomiphene-placebo | OTHER | anastrozole for eight weeks then clomiphene for eight weeks then placebo for eight weeks |
| anastrazole-placebo-clomiphene | OTHER | anastrozole for eight weeks then placebo for eight weeks then clomiphene for eight weeks |
| clomiphene-anastrazole-placebo | OTHER | clomiphene for eight weeks then anastrozole for eight weeks then placebo for eight weeks |
| clomiphene-placebo-anastrazole | OTHER | clomiphene for eight weeks then placebo for eight weeks then anastrozole for eight weeks |
| placebo-clomiphene-anastrazole | OTHER | placebo for eight weeks then clomiphene for eight weeks then anastrozole for eight weeks |
| placebo-anastrazole-clomiphene | OTHER | placebo for eight weeks then anastrozole for eight weeks then clomiphene for eight weeks |
| Name | Type | Description |
|---|---|---|
| Anastrozole 1mg | DRUG | - |
| Clomiphene Citrate 25mg | DRUG | - |
| Placebo - Cap | DRUG | - |
Inclusion Criteria: 1. Men age 18-70 2. Baseline morning Testosterone 150-350 ng/dL x2 3. leutenizing hormone (LH) 1.5-9.2 miU/mL, Follicle stimulation hormone (FSH) 1.6-8.0 miU/mL, Prolactin 4-15 ng/mL 4. Positive Androgen Deficiency in the Aging Male (ADAM) score. A positive score is when an affi...