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PRX-100

Phase 2

Presbyopia | Small molecule | Ophthalmology |LENZ Therapeutics, Inc.|Last Updated: Oct 23, 2017

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLED
Total Trials1
Total Enrollment20

FDA Designations

No designations recorded

Clinical trial landscape

PRX-100 · 1 trial · 1 indication

Phase 2 1
NCT02554396Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate PresbyopiaPresbyopia
COMPLETED20 Analytics
PHASE2COMPLETED
Evaluation of the Efficacy and Safety of PRX-100 in the Treatment of Early to Moderate Presbyopia
PresbyopiaUnlock trial analytics

Study Endpoints

Primary Endpoints

binocular assessment of uncorrected near visual acuity
day 1

Secondary Endpoints

pupil diameter
day 1
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
PRX-100EXPERIMENTALPRX-100 ophthalmic solution
PlaceboPLACEBO_COMPARATORsaline solution

Interventions

NameTypeDescription
PRX-100DRUGophthalmic solution
PlaceboDRUGsaline ophthalmic solution
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Eligibility Criteria

Age Range45 Years to 59 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: 1. be 45-59 years of age of either sex and any race or ethnicity; 2. be able and willing to provide written informed consent and sign HIPAA form prior to any study procedure being performed; 3. be able and willing to follow all instructions and attend all study visits; 4. have a...

Countries:United States
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Frequently asked questions about PRX-100

What is PRX-100 used for?

PRX-100 is an investigational small molecule being developed for the treatment of presbyopia, an age-related condition that affects the eye's ability to focus on close objects. It is intended for use in patients with early to moderate presbyopia. The drug is currently in clinical development and has not been approved by regulatory authorities.

Who makes PRX-100?

PRX-100 is being developed by LENZ Therapeutics, Inc., a biopharmaceutical company. The company's stock is traded under the ticker symbol LENZ. LENZ Therapeutics is responsible for the clinical development and potential commercialization of PRX-100 for the treatment of presbyopia.

What phase is PRX-100 in?

PRX-100 is in Phase 2 clinical development. A Phase 2 clinical trial evaluating the efficacy and safety of PRX-100 in the treatment of early to moderate presbyopia has been completed. The drug is investigational and has not been approved by the FDA or other regulatory agencies.

What clinical trials is PRX-100 in?

PRX-100 has been studied in one completed Phase 2 clinical trial with the identifier NCT02554396. This trial was a randomized, double-blind, placebo-controlled study that evaluated the efficacy and safety of PRX-100 in the treatment of early to moderate presbyopia. The trial enrolled 20 participants in the United States.

How does PRX-100 work?

PRX-100 is a small molecule designed to treat presbyopia, a condition that impairs near vision. The specific molecular target of PRX-100 has not been disclosed. The drug is being developed to address the visual symptoms of presbyopia, which typically worsen with age.