Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT02137590 | An Open Label Pilot Study to Evaluate the Efficacy of Spanish Black Radish on the Induction of Phase I and Phase II Enzymes | PHASE1 | COMPLETED | 20 | — | — | Sep 1, 2011 | Nov 1, 2011 | May 14, 2014 | 1 | Canada |
The effect on phase I and phase II enzyme activity determined by measuring plasma and urine acetaminophen metabolite concentrations Subjects will ingest 1000 mg of acetaminophen. Blood will be collected at 0, 2, 4, 6 and 8 hours after acetaminophen dosage for the analysis of plasma acetaminophen metabolites. These measurements will be performed prior to and after 4 weeks of treatment with Spanish Black Radish product.
| Arm | Type | Description |
|---|---|---|
| Spanish Black Radish | EXPERIMENTAL | Spanish Black Radish product |
| Name | Type | Description |
|---|---|---|
| Spanish Black Radish product | DIETARY_SUPPLEMENT | - |
Inclusion Criteria: * Male age 25 - 35 years * BMI 18 - 25 kg/m2 * Healthy as determined by laboratory results, medical history * Agrees to avoid the consumption of cruciferous vegetables for 14 days prior to baseline and during the study treatment period * Has given voluntary, written, informed co...