Recent Updates
Recently added Catalysts

JADE201

Phase 1

Rhematoid Arthritis | Small molecule | Other |Jade Biosciences, Inc.|Last Updated: Jun 1, 2026

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
RandomizedDouble-BlindCONTROLLEDBiomarker
Total Trials1
Total Enrollment36
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT07533955A Phase 1 Study of JADE201 in Participants With Rheumatoid ArthritisPHASE1 RECRUITING 36May 19, 2026Oct 1, 2028Jun 1, 20263 Moldova, Ukraine
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
Safety and Tolerability of Single Ascending Doses of JADE201 in participants with Rheumatoid Arthritis
Day 1 through 36 weeks

Incidence of treatment-emergent adverse events

Secondary Endpoints
Cmax
Day 1 through Weeek 36
Tmax
Day 1 through Week 36
AUClast
Day 1 through Week 36
Unlock Study Endpoints
Study Design & Arms
AllocationRANDOMIZED
MaskingDOUBLE
ModelSEQUENTIAL
PurposeBASIC_SCIENCE
Treatment Arms
ArmTypeDescription
JADE201EXPERIMENTALSubcutaneous (SC) injection of JADE201
PlaceboEXPERIMENTALSubcutaneous (SC) injection of Placebo
Interventions
NameTypeDescription
JADE201DRUGJADE201 is supplied as sterile solution to be administered by SC injection.
PlaceboDRUGPlacebo solution to be administered at a matching volume by SC injection.
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — 70 Years
SexALL
Healthy VolunteersNo
Study Sites3

Inclusion Criteria: 1. Male and female participants 18-70 years of age, inclusive. 2. A body weight between 50-100 kg and a body mass index (BMI) between 18-32 kg/m2 (all inclusive) at screening. 3. Confirmed diagnosis of RA according to 2010 ACR/EULAR criteria 4. Willing and able to comply with th...

Countries:MoldovaUkraine
Unlock Eligibility Criteria
Recent Changes (Last 90 Days)
LOWJun 2, 2026NCT07533955Status: NOT_YET_RECRUITING → RECRUITING
LOWJun 2, 2026NCT07533955Status: NOT_YET_RECRUITING → RECRUITING
LOWJun 2, 2026NCT07533955Status: NOT_YET_RECRUITING → RECRUITING
LOWMay 26, 2026NCT07533955primaryCompletionDate: changed
LOWMay 24, 2026NCT07533955studyFirstPostDate: changed
LOWMay 21, 2026NCT07533955NEW_TRIAL: changed
LOWMay 21, 2026NCT07533955NEW_TRIAL: changed