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ISIS 14803, peginterferon alfa, ribavirin

Phase 2

Hepatitis C, Chronic | Small molecule | Infectious Disease |Ionis Pharmaceuticals, Inc.|Last Updated: Dec 5, 2022

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLEDBiomarker
Total Trials2
Total Enrollment22
FDA Designations
No designations recorded
Clinical Trials (2)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT00035945ISIS 14803-CS2, Treatment With ISIS 14803, Administered IV in Patients With Chronic Hepatitis C Virus InfectionsPHASE2 COMPLETED -Oct 1, 2001May 1, 2004Dec 5, 20221 United States
NCT00062816Addition of ISIS 14803 to Therapy With Peginterferon and Ribavirin for Chronic Hepatitis C (HCV) Patients Not Responding Adequately to the Two DrugsPHASE1 COMPLETED 22Jun 1, 2003Jan 1, 2004Dec 5, 202225 United States
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Study Design & Arms
PurposeTREATMENT
Interventions
NameTypeDescription
ISIS 14803DRUG -
ISIS 14803, peginterferon alfa, ribavirinDRUG -
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria Patients must meet the following inclusion criteria during screening: * Age greater than or equal to 18 years. * Both males and females are eligible. All patients should be advised that there are no data on the possible reproductive (teratological) effects of ISIS 14803. Theref...

Countries:United States
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