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INO-3401+ EP

Phase 1

Healthy | Monoclonal antibody | Other |Inovio Pharmaceuticals, Inc.|Last Updated: Sep 13, 2017

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment22

FDA Designations

No designations recorded

Clinical trial landscape

INO-3401+ EP · 1 trial · 1 indication

Phase 1 1
NCT01403155A Follow-On Study With an H5 Influenza Vaccine for Subjects Who Participated in Study FLU-001Healthy
COMPLETED22 Analytics
PHASE1COMPLETED
A Follow-On Study With an H5 Influenza Vaccine for Subjects Who Participated in Study FLU-001
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Study Endpoints

Primary Endpoints

Safety
Day 0 through Month 9

Frequency and severity of local and systemic reactogenicity, signs and symptoms, adverse events and serious adverse events.

Secondary Endpoints

Humoral and cellular immune responses
Day 0 through Month 9
Tolerability
Day 0 and Month 3
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposePREVENTION

Treatment Arms

ArmTypeDescription
All subjectsEXPERIMENTALAll subjects will receive 0.9mg/mL of study vaccine (INO-3401 DNA plasmid vaccine) at Day o and Month 3.

Interventions

NameTypeDescription
INO-3401 + EPBIOLOGICALAll subjects will receive 0.9mg/mL of study vaccine (INO-3401 DNA plasmid vaccine)at Day 0 and Month 3.
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Eligibility Criteria

Age Range18 Years to 50 Years
SexALL
Healthy VolunteersYes
Study Sites2

Inclusion Criteria: * Written informed consent in accordance with institutional guidelines. If required by local law, candidates must also authorize the release and use of protected health information (PHI); * Enrollment in and received at least one vaccination in study FLU-001; * Adults of either ...

Countries:United States
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Frequently asked questions about INO-3401+ EP

What is INO-3401+ EP used for?

INO-3401+ EP is an investigational product studied in healthy volunteers. It was evaluated in a Phase 1 clinical trial as a follow-on H5 influenza vaccine for subjects who previously participated in study FLU-001. The trial enrolled 22 participants in the United States.

Who makes INO-3401+ EP?

INO-3401+ EP is developed by Inovio Pharmaceuticals, Inc., a biopharmaceutical company traded on the NASDAQ under the ticker symbol INO. The company conducted a Phase 1 clinical trial of this product in healthy volunteers in the United States.

What phase is INO-3401+ EP in?

INO-3401+ EP is in Phase 1 clinical development. It is an investigational product and has not been approved by regulatory authorities. The Phase 1 trial, NCT01403155, has been completed, and the product remains in early-stage clinical investigation.

What clinical trials is INO-3401+ EP in?

INO-3401+ EP was studied in one completed Phase 1 clinical trial, NCT01403155, titled 'A Follow-On Study With an H5 Influenza Vaccine for Subjects Who Participated in Study FLU-001.' The trial enrolled 22 healthy volunteers in the United States and was not randomized or double-blinded.

Is INO-3401+ EP a monoclonal antibody?

INO-3401+ EP is classified as a monoclonal antibody modality. It was evaluated as an H5 influenza vaccine in a Phase 1 follow-on study for healthy subjects who had previously participated in study FLU-001. The trial enrolled 22 participants in the United States.