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INCB13739

Phase 1

Insulin Resistance | Small molecule | Metabolic |Incyte Corporation|Last Updated: Jan 23, 2012

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment -

FDA Designations

No designations recorded

Clinical trial landscape

INCB13739 · 1 trial · 2 indications

Phase 1 1
NCT00398619A Study of the Effect of INCB013739 on Cortisone Reducing Enzyme Activity in Obese People Predisposed to DiabetesInsulin Resistance
COMPLETED- Analytics
PHASE1COMPLETED
A Study of the Effect of INCB013739 on Cortisone Reducing Enzyme Activity in Obese People Predisposed to Diabetes
Insulin ResistanceUnlock trial analytics

Study Endpoints

Primary Endpoints

Assessment of pharmacokinetics of INCB013739 through analysis of blood samples.
Serial collections at each visit
Evaluation of change in cortisol laboratory values
Serial collections at each visit
Assessment of ECGs, laboratory results and physical exams for adverse events
Measured from baseline through study completion
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
INCB13739DRUG -
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites2

Inclusion Criteria: * Male and female subjects between 18 years and 65 years of age. * BMI between 30 and 42 kg/m2, inclusive. * FPG \<126 mg/dL Exclusion Criteria: * Meet criteria for diagnosis of diabetes mellitus at the screening evaluation, female subjects with a history of gestational diabet...

Countries:United States
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Frequently asked questions about INCB13739

What is INCB13739 used for?

INCB13739 is an investigational small molecule being developed for insulin resistance, a metabolic condition. It was studied in a Phase 1 clinical trial in obese people predisposed to diabetes, with the aim of evaluating its effect on cortisone reducing enzyme activity. The drug is not approved and remains in clinical development.

Who makes INCB13739?

INCB13739 is developed by Incyte Corporation, a biopharmaceutical company traded on the NASDAQ under the ticker INCY. Incyte is conducting clinical research on this investigational small molecule for the treatment of insulin resistance.

What phase is INCB13739 in?

INCB13739 is in Phase 1 clinical development. It has completed one Phase 1 trial, which was a randomized, double-blind, uncontrolled study. The drug is investigational and has not been approved by regulatory authorities.

What clinical trials is INCB13739 in?

INCB13739 has one completed clinical trial, identified as NCT00398619. The study, titled 'A Study of the Effect of INCB013739 on Cortisone Reducing Enzyme Activity in Obese People Predisposed to Diabetes,' was a Phase 1 trial conducted in the United States in adults with insulin resistance and obesity.

Is INCB13739 the same as INCB013739?

Yes, INCB13739 is also known as INCB013739. The clinical trial NCT00398619 uses the name INCB013739 in its title, while the drug is referred to as INCB13739 in other contexts. Both names refer to the same investigational small molecule.