Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT02226562 | Clinical Study Investigating the Efficacy of a Mouthwash in Providing Long Term Relief From Dentinal Hypersensitivity | PHASE2 | COMPLETED | 191 | — | — | Sep 2, 2014 | Dec 5, 2014 | Aug 27, 2018 | 1 | United States |
The examiner indicated the participant's response to an evaporaitve air stimulus for each tooth using the Schiff Sensitivity Scale scored as follows - 0: Participant does not respond to air stimulation; 1: responds to air stimulus but does not request discontinuation of stimulus; 2: Participant responds to air stimulus and requests discontinuation or moves from stimulus; 3: Participant responds to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus. A reduction in Schiff Sensitivity score is indicative of an imrpovement in sensitivity.
| Arm | Type | Description |
|---|---|---|
| Potassium nitrate and sodium fluoride | EXPERIMENTAL | 3.0% weight by weight (w/w) potassium nitrate mouthwash with 0.02% sodium fluoride |
| Standard fluoride dentifrice | OTHER | Standard fluoride dentifrice containing 1000 ppm fluoride as sodium monofluorophosphate (SMFP) |
| Name | Type | Description |
|---|---|---|
| Potassium nitrate and sodium fluoride | DRUG | 3.0% w/w potassium nitrate mouthwash with 0.02% sodium fluoride |
| Standard fluoride dentifrice | DRUG | Standard fluoride dentifrice containing 1000 ppm fluoride as SMFP |
Inclusion Criteria: * Participants in good general health, with self-reported history of dentinal hypersensitivity lasting more than 6 months but not more than 10 years. * Participants with minimum of 20 natural teeth. * At screening, a minimum of four, non-adjacent teeth. 1. Teeth showing signs...