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SB683699

Phase 2

Multiple Sclerosis, Relapsing-Remitting | Small molecule | Neurology |GSK plc|Last Updated: Apr 13, 2015

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment261

FDA Designations

No designations recorded

Clinical trial landscape

SB683699 · 1 trial · 1 indication

Phase 2 1
NCT00097331Three Months Treatment With SB683699 In Patients With Relapsing Multiple SclerosisMultiple Sclerosis, Relapsing-Remitting
COMPLETED261 Analytics
PHASE2COMPLETED
Three Months Treatment With SB683699 In Patients With Relapsing Multiple Sclerosis
Multiple Sclerosis, Relapsing-RemittingUnlock trial analytics

Study Endpoints

Primary Endpoints

Number of new gadolinium-enhancing lesions on monthly MRI scans

Secondary Endpoints

Number of other lesion types on MRI
Number of relapses during treatment
Expanded Disability Status Scale (EDSS) and MS Functional Composite (MSFC)
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Interventions

NameTypeDescription
SB683699DRUG -
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites11

Inclusion criteria: * Diagnosis of multiple sclerosis (MS). * Expanded Disability Status Score 0 - 6.5. * One or more relapse of MS in previous 12 months. * Currently not taking any medications for MS (apart from those used to treat symptoms). Exclusion criteria: * Patients with significantly abn...

Countries:BelgiumGermanyPolandRussiaSpain
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Frequently asked questions about SB683699

What is SB683699 used for?

SB683699 is an investigational small molecule being studied for the treatment of relapsing-remitting multiple sclerosis, a form of multiple sclerosis characterized by episodes of neurologic symptoms followed by periods of remission. It is in Phase 2 clinical development and is not yet approved by regulatory authorities.

Who is developing SB683699?

SB683699 is being developed by GSK plc, a global biopharmaceutical company traded on the London Stock Exchange under the ticker GSK. The company is conducting clinical trials to evaluate the safety and efficacy of this investigational drug in patients with relapsing-remitting multiple sclerosis.

What phase is SB683699 in?

SB683699 is in Phase 2 clinical development. A Phase 2 trial has been completed, which evaluated the drug in patients with relapsing-remitting multiple sclerosis. The drug remains investigational and has not received regulatory approval for any indication.

What clinical trials is SB683699 in?

SB683699 has been studied in one completed Phase 2 clinical trial, identified as NCT00097331. This trial, titled "Three Months Treatment With SB683699 In Patients With Relapsing Multiple Sclerosis," enrolled 261 participants across Belgium, Germany, Poland, Russia, and Spain. The trial was randomized and double-blind.

Is SB683699 FDA approved?

SB683699 is not FDA approved. It is an investigational drug currently in Phase 2 clinical development for relapsing-remitting multiple sclerosis. The completed Phase 2 trial, NCT00097331, has finished, but the drug has not yet received marketing authorization from regulatory agencies.