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SB-743921

Phase 1

Solid Tumor Cancer | Small molecule | Oncology |GSK plc|Last Updated: Oct 16, 2008

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment30

FDA Designations

No designations recorded

Clinical trial landscape

SB-743921 · 1 trial · 1 indication

Phase 1 1
NCT00136513SB-743921 In Patients With Solid TumorsSolid Tumor Cancer
COMPLETED30 Analytics
PHASE1COMPLETED
SB-743921 In Patients With Solid Tumors
Solid Tumor CancerUnlock trial analytics

Study Endpoints

Primary Endpoints

Safety and tolerability will include evaluation of adverse events (AE) and changes from baseline in vital signs and clinical laboratory parameters. PK endpoints will include Cl, Vd, AUC, Cmax, and t½.

Secondary Endpoints

Tumor response Comparison of pre and post-dose biomarker levels and/or correlation of pre-dose biomarker levels to any subsequent tumor response.
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
SB-743921DRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites2

Inclusion criteria: * Histologically or cytologically confirmed diagnosis of: a) Advanced solid tumor malignancy that is not responsive to standard therapies or for which there is no standard therapy; OR b) B-cell or T-cell lymphoma (excluding HIV-associated lymphoma) that has relapsed or is refrac...

Countries:United States
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Frequently asked questions about SB-743921

What is SB-743921 used for?

SB-743921 is an investigational small molecule being studied for the treatment of solid tumor cancer. It is currently in Phase 1 clinical development, meaning it has not yet been approved by regulatory authorities and remains under investigation for safety and efficacy in patients.

Who makes SB-743921?

SB-743921 is being developed by GSK plc, a pharmaceutical company listed on the stock exchange under the ticker symbol GSK. The company is conducting clinical research to evaluate the drug's potential in oncology.

What phase is SB-743921 in?

SB-743921 is in Phase 1 clinical development. It is an investigational drug, not yet approved, and is being studied for the treatment of solid tumor cancer. The Phase 1 trial has been completed, and the drug remains under investigation.

What clinical trials is SB-743921 in?

SB-743921 has been studied in one clinical trial, identified as NCT00136513, titled "SB-743921 In Patients With Solid Tumors." This Phase 1 trial was completed in the United States and enrolled 30 adult patients with solid tumor cancer.

Is SB-743921 FDA approved?

SB-743921 is not FDA approved. It is an investigational drug currently in Phase 1 clinical development for solid tumor cancer. The completed Phase 1 trial, NCT00136513, was an uncontrolled study, and the drug has not yet received regulatory approval.