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Radiolabelled GSK189075

Phase 1

Type 2 Diabetes Mellitus | Small molecule | Metabolic |GSK plc|Last Updated: Jun 4, 2012

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment8

FDA Designations

No designations recorded

Clinical trial landscape

Radiolabelled GSK189075 · 1 trial · 2 indications

Phase 1 1
NCT00501683A Single Dose Of GSK189075 Taken By Mouth Containing Small Amounts Of Radioactivity Studied In Healthy Male VolunteersType 2 Diabetes Mellitus
COMPLETED8 Analytics
PHASE1COMPLETED
A Single Dose Of GSK189075 Taken By Mouth Containing Small Amounts Of Radioactivity Studied In Healthy Male Volunteers
Type 2 Diabetes MellitusUnlock trial analytics

Study Endpoints

Primary Endpoints

Laboratory tests to determine the amount of radiolabelled drug that is found in blood, urine, and feces. Blood samples at Days 1-5.
at Days 1-5.
Urine & Fecal collection at Day -1 & days 1-5.
at Day -1 & days 1-5.

Secondary Endpoints

Adverse events (AEs), vital signs, ECGs and clinical laboratory assessments at each day for up to 10 days
at each day for up to 10 days
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Study Design & Arms

AllocationNON_RANDOMIZED
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Interventions

NameTypeDescription
Radiolabelled GSK189075DRUG -
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Eligibility Criteria

Age Range30 Years to 55 Years
SexMALE
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Are a healthy, non-smoking male. * Are 30 to 55 years old, inclusive. * Have a Body Mass Index (BMI) between 19-30 kg/m2, inclusive; and a body weight \>110 lbs. * Have a history of regular bowel movements (at least 4 times per week). * Are willing and able to provide written ...

Countries:United States
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Frequently asked questions about Radiolabelled GSK189075

What is Radiolabelled GSK189075 used for?

Radiolabelled GSK189075 is an investigational small molecule being studied for Type 2 Diabetes Mellitus. It is a radiolabelled form of GSK189075, intended for use in a clinical trial to track the drug's behavior in the body. It is in Phase 1 clinical development and is not yet approved.

Who makes Radiolabelled GSK189075?

Radiolabelled GSK189075 is being developed by GSK plc, traded on the stock exchange under the ticker GSK. The company is conducting clinical research on this investigational drug for the treatment of Type 2 Diabetes Mellitus.

What phase is Radiolabelled GSK189075 in?

Radiolabelled GSK189075 is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. The Phase 1 trial has been completed, and the drug remains under clinical investigation.

What clinical trials is Radiolabelled GSK189075 in?

Radiolabelled GSK189075 has one completed clinical trial, identified as NCT00501683. This Phase 1 study, titled 'A Single Dose Of GSK189075 Taken By Mouth Containing Small Amounts Of Radioactivity Studied In Healthy Male Volunteers,' enrolled 8 participants in the United States.

Is Radiolabelled GSK189075 the same as GSK189075?

Radiolabelled GSK189075 is a radiolabelled version of GSK189075, meaning it contains a small amount of radioactivity for tracking purposes in clinical studies. It is used to study the pharmacokinetics of GSK189075 in the body, specifically in a Phase 1 trial involving healthy male volunteers.