Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT01277081 | Effect of Paracetamol on the Common Cold | PHASE2 | COMPLETED | 200 | — | — | Oct 1, 2010 | Dec 1, 2010 | Feb 18, 2015 | 1 | United Kingdom |
A mean breathing score was calculated at baseline, 30 seconds, 2, 5 and 15 minutes, derived from participant responses to questions relating to breathing i.e. "my breathing feels easy", "I feel airways are open", "I feel a cooling sensation in my throat", "I can feel the air flowing to my lungs easily", "My nose feels less blocked" and "I feel my breathing is comfortable". The breathing scores were rated by the participants on a 5 point (0-4) rating scale with '0' being labeled as 'strongly disagree' and '4' being labeled as 'strongly agree'. For each participant, a mean score was derived by summing the responses and dividing by the number of questions answered.
| Arm | Type | Description |
|---|---|---|
| Paracetamol hot drink | ACTIVE_COMPARATOR | Hot drink containing paracetamol |
| Paracetamol tablets | ACTIVE_COMPARATOR | Paracetamol tablets |
| Name | Type | Description |
|---|---|---|
| Paracetamol hot drink | DRUG | Hot drink containing paracetamol |
| Paracetamol tablets | DRUG | Paracetamol tablets |
Inclusion Criteria: * Symptoms of the common cold of no more than 120 hours duration * Self-rating congestion of at least moderate severity * Suffering from at least four symptoms of common cold or flu