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GSK945237

Phase 1

Healthy Subjects | Small molecule | Infectious Disease |GSK plc|Last Updated: Mar 19, 2012

Success Probability

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Market & Valuation

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Trial Design

RandomizedPLACEBO_CONTROLLED
Total Trials1
Total Enrollment68

FDA Designations

No designations recorded

Clinical trial landscape

GSK945237 · 1 trial · 2 indications

Phase 1 1
NCT00517673To Evaluate Safety, Tolerability, Pharmacokinetics, And Food Effect Of Single Doses Of GSK945237 In Healthy SubjectsHealthy Subjects
COMPLETED68 Analytics
PHASE1COMPLETED
To Evaluate Safety, Tolerability, Pharmacokinetics, And Food Effect Of Single Doses Of GSK945237 In Healthy Subjects
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Study Endpoints

Primary Endpoints

Safety and tolerability
Day 1 to follow-up visit

Secondary Endpoints

Pharmacokinetics
Day 1 to Day 5
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Study Design & Arms

AllocationRANDOMIZED
MaskingSINGLE
ModelPARALLEL

Treatment Arms

ArmTypeDescription
GSK945237EXPERIMENTALActive Study Drug
Sugar PillPLACEBO_COMPARATORPlacebo

Interventions

NameTypeDescription
GSK945237DRUG -
Sugar PillDRUGPlacebo
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Eligibility Criteria

Age Range18 Years to 60 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Healthy male and female adults between 18 and 60 years of age. * Body weight proportional to height. * Female subjects must be of non-childbearing potential. * QTc less than 450 msec at screening Exclusion Criteria: * Any clinically relevant abnormality identified on the scr...

Countries:Australia
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Frequently asked questions about GSK945237

What is GSK945237 used for?

GSK945237 is an investigational small molecule being studied for use in healthy subjects and for bacterial infections. It is in Phase 1 clinical development, and the completed trial evaluated the drug in healthy volunteers to assess safety, tolerability, pharmacokinetics, and the effect of food on single doses.

Who makes GSK945237?

GSK945237 is being developed by GSK plc, a global biopharmaceutical company. GSK plc is listed on the stock exchange under the ticker symbol GSK.

What phase is GSK945237 in?

GSK945237 is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. The Phase 1 trial has been completed, and the drug is no longer in active clinical trials.

What clinical trials is GSK945237 in?

GSK945237 has one completed Phase 1 clinical trial, identified as NCT00517673. This trial evaluated the safety, tolerability, pharmacokinetics, and food effect of single doses of GSK945237 in healthy subjects. The trial enrolled 68 participants in Australia and was placebo-controlled.

Is GSK945237 FDA approved?

GSK945237 is not FDA approved. It is an investigational drug that has completed a Phase 1 clinical trial in healthy subjects. The drug is still in clinical development and has not been approved for any use.