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GSK580416

Phase 1

Respiratory Tract Infection | Small molecule | Infectious Disease |GSK plc|Last Updated: Jun 4, 2012

Success Probability

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Market & Valuation

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Trial Design

RandomizedUNCONTROLLED
Total Trials1
Total Enrollment48

FDA Designations

No designations recorded

Clinical trial landscape

GSK580416 · 1 trial · 2 indications

Phase 1 1
NCT00427141A Three-Part Study Of GSK580416 In Healthy SubjectsRespiratory Tract Infection
COMPLETED48 Analytics
PHASE1COMPLETED
A Three-Part Study Of GSK580416 In Healthy Subjects
Respiratory Tract InfectionUnlock trial analytics

Study Endpoints

Primary Endpoints

Safety assessments (adverse event, ECG and vital sign) will be performed during the study. Blood samples to determine drug levels in the body will be collected during the study.
during the study

Secondary Endpoints

Blood samples to determine drug levels in the body will be collected during the study.
during the study
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Study Design & Arms

AllocationRANDOMIZED
MaskingSINGLE
ModelCROSSOVER
PurposeTREATMENT

Interventions

NameTypeDescription
GSK580416DRUG -
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Eligibility Criteria

Age Range18 Years to 55 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion criteria: * Healthy as determined by a physician * Healthy male or female of non-child bearing potential between 18 and 55 years of age (inclusive) * Body weight \> = 50 kg and BMI between 19 and 30 kg/m2 (inclusive) Exclusion criteria: * Positive HIV antibody, Hepatitis B surface antig...

Countries:Australia
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Frequently asked questions about GSK580416

What is GSK580416 used for?

GSK580416 is an investigational small molecule being developed by GSK plc for the treatment of Respiratory Tract Infection. It is currently in Phase 1 clinical development, meaning it has not yet been approved by regulatory authorities and is still being evaluated for safety and tolerability in humans.

Who makes GSK580416?

GSK580416 is being developed by GSK plc, a global biopharmaceutical company listed on the stock exchange under the ticker GSK. The drug is an investigational small molecule intended for use in Respiratory Tract Infection and is currently in Phase 1 clinical trials.

What phase is GSK580416 in?

GSK580416 is in Phase 1 clinical development. It is an investigational drug, not yet approved by the FDA or other regulatory agencies. The Phase 1 trial has been completed, and the drug remains in early-stage clinical development for Respiratory Tract Infection.

What clinical trials is GSK580416 in?

GSK580416 has one completed Phase 1 clinical trial, identified as NCT00427141, titled "A Three-Part Study Of GSK580416 In Healthy Subjects." This trial enrolled 48 participants in Australia, was randomized but not double-blind, and had no control group. The study focused on healthy volunteers aged 18 years and older.

Is GSK580416 FDA approved?

No, GSK580416 is not FDA approved. It is an investigational drug currently in Phase 1 clinical development for Respiratory Tract Infection. The Phase 1 trial has been completed, but the drug has not yet progressed to later-stage trials or received regulatory approval.

Is GSK580416 a small molecule?

Yes, GSK580416 is a small molecule drug. It is being developed by GSK plc as an investigational treatment for Respiratory Tract Infection and is currently in Phase 1 clinical development. The completed Phase 1 trial enrolled healthy volunteers to assess the drug's safety and tolerability.