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GSK369796

Phase 1

Malaria | Small molecule | Infectious Disease |GSK plc|Last Updated: Sep 13, 2018

Success Probability

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Market & Valuation

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Trial Design

RandomizedACTIVE_CONTROLLED
Total Trials1
Total Enrollment41

FDA Designations

No designations recorded

Clinical trial landscape

GSK369796 · 1 trial · 1 indication

Phase 1 1
NCT00675064Single-Blind, Placebo-Controlled, Randomized Study Testing Single Ascending Doses Of GSK369796 In Healthy SubjectsMalaria
COMPLETED41 Analytics
PHASE1COMPLETED
Single-Blind, Placebo-Controlled, Randomized Study Testing Single Ascending Doses Of GSK369796 In Healthy Subjects
MalariaUnlock trial analytics

Study Endpoints

Primary Endpoints

Safety and tolerability
From Day 1 to follow-up visit

Secondary Endpoints

Pharmacokinetics
Day 1 to Day 4
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Study Design & Arms

AllocationRANDOMIZED
MaskingSINGLE
ModelPARALLEL
PurposeOTHER

Treatment Arms

ArmTypeDescription
Anti-malarial experimental drugEXPERIMENTALAfter randomization subjects will receive either 5, 25, 100, 250, 500, 1000, 2000 and 3000 mg of GSK3697969 orally . GSK3697969 will be available as 5, 25 and 250 mg capsules.
Matching placeboACTIVE_COMPARATORAfter randomization subjects will receive matching placebo of GSK3697969.

Interventions

NameTypeDescription
GSK369796DRUGAnti-malarial
PlaceboDRUGPlacebo matching GSK369796
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Eligibility Criteria

Age Range18 Years to 40 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Healthy adults between the ages of 18 to 40, inclusive. * Female subjects must be of non-childbearing potential including pre-menopausal females with documented (medical report verification) hysterectomy or bilateral oophrectomy or postmenopausal defined as 6 months of spontan...

Countries:United Kingdom
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Competitive Landscape -Malaria 6 trials

Frequently asked questions about GSK369796

What is GSK369796 used for?

GSK369796 is an investigational small molecule being developed for the treatment of malaria. It is currently in Phase 1 clinical development and has not been approved by regulatory authorities. The drug is being studied in healthy volunteers to evaluate its safety and tolerability.

What does GSK369796 target?

The specific molecular target of GSK369796 has not been disclosed. The drug is being developed as a small molecule for malaria, but its mechanism of action is not publicly detailed in the available clinical trial information.

Who makes GSK369796?

GSK369796 is being developed by GSK plc, a global biopharmaceutical company listed on the stock exchange under the ticker GSK. The company is conducting clinical trials to evaluate the drug's safety and pharmacokinetics in healthy subjects.

What phase is GSK369796 in?

GSK369796 is in Phase 1 clinical development. A single Phase 1 trial has been completed, involving 41 healthy volunteers in the United Kingdom. The drug remains investigational and has not yet received regulatory approval for any indication.

What clinical trials is GSK369796 in?

GSK369796 has one completed clinical trial registered as NCT00675064, a single-blind, placebo-controlled, randomized study testing single ascending doses in healthy subjects. The trial enrolled 41 participants in the United Kingdom and was completed, with no active trials currently ongoing.

Is GSK369796 the same as any other drug?

No alternative names for GSK369796 have been disclosed. The drug is identified solely by its development code GSK369796 in clinical trial registrations and scientific literature. It is not known to be marketed under any other brand name.