Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
| NCT ID | Title | Phase | Status | Enrollment | Velocity | Design | Start | Completion | Last Updated | Sites | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|
| NCT02058654 | A Clinical Study to Investigate the Effects of Creatine Supplementation on Muscle Energetics and Cognitive Function in Young Healthy Male Athletes and an Ageing Population | PHASE1 | COMPLETED | 30 | — | — | Dec 1, 2013 | Jun 24, 2014 | Mar 23, 2018 | 1 | United Kingdom |
Change in PCr concentration (at rest), as measured by 31P- MRS on the calf. Static MRS will be acquired at rest up to 2 min.
| Arm | Type | Description |
|---|---|---|
| Creatine Group | EXPERIMENTAL | Whey protein (30 g) and creatine supplement (5 g) shaken with 250-300 ml water in a blender bottle, and the full shake to be taken twice a day for 14 days. |
| Placebo Group | PLACEBO_COMPARATOR | Whey protein (30 g) and bulking agent powder (5 g) shaken with 250-300 ml water in a blender bottle, and the full shake to be taken twice a day for 14 days. |
| Name | Type | Description |
|---|---|---|
| Creatine | DRUG | Creatine powder (5 g) |
| Placebo | DRUG | Bulking agent powder (5 g) |
Inclusion Criteria: * Healthy volunteer: Group 1: male; Group 2: male or female. * Aged 18-35 years (Group 1), or 50-70 years (Group 2). * Dietary protein intake at or near the current recommended daily amount (0.75 to 0.85 g protein/kg/day). * Participation in regular physical activity (aerobic an...