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Carbon Dioxide

Phase 2

Nasal Congestion | Small molecule | ENT |GSK plc|Last Updated: Apr 30, 2015

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment147

FDA Designations

No designations recorded

Clinical trial landscape

Carbon Dioxide · 1 trial · 1 indication

Phase 2 1
NCT02113449Market Potential of Carbon Dioxide Nasal SprayNasal Congestion
COMPLETED147 Analytics
PHASE2COMPLETED
Market Potential of Carbon Dioxide Nasal Spray
Nasal CongestionUnlock trial analytics

Study Endpoints

Primary Endpoints

Which One Product That Relieves Nasal Congestion do You Buy Most Often?
7 days

There was one questionnaire used in this study which was divided into 3 parts: screening survey, after product trial questions, and at home usage experience. This question was asked as part of screening survey prior to concept viewing. If the participant answered "I do not purchase any product to relieve congestion" the participant was excluded. Participants could select only one option available.

Which of the Statements Best Describes the Extent to Which the Spray Reached Your Expectations?
7 days

There was one questionnaire used in this study which was divided into 3 parts: screening survey, after product trial questions, and at home usage experience. This question was asked after the first use. Participants could select only one option.

If the Product You Just Tried (After First Dose) Was Available for the Following Price: $12.99 for 40 Doses, How Likely Would You be to Buy it?
7 days

There was one questionnaire used in this study which was divided into 3 parts: screening survey, after product trial questions, and at home usage experience. This question was asked after the first dose of the product. Participants could select only one option.

Would You be Interested in Taking the Spray Product Home and Using it Over the Next Week?
7 days

There was one questionnaire used in this study which was divided into 3 parts: screening survey, after product trial questions, and at home usage experience. This question was asked after the first dose of the product. Participants could select only one option.

Which of the Following Statements Best Describes the Extent to Which the Spray Reached Your Expectations?
7 days

There was one questionnaire used in this study which was divided into 3 parts: screening survey, after product trial questions, and at home usage experience. This question was asked after at-home use of the product. Participants could select only one option.

Divide 11 Points Between Two Products (CO2 Nasal Spray and Brand Selected at Q1)?
7 days

There was one questionnaire used in this study which was divided into 3 parts: screening survey, after product trial questions, and at home usage experience. This question was asked after at-home use of the product. Participants could select only one option. It was done to compare the spray with the product selected by the participant in Q1. There were 11 points between the two products that participants could divide anyways thet wanted (11-0, 10-1, 9-2, 8-3, 7-4 or 6-5 etc). The more the participant liked a product compared to other, the higher the number of points were to be given to that product.

If the Product You Just Tried (After At-home Use) Was Available for the Following Price: $12.99 for 40 Doses, How Likely Would You be to Buy it?
7 days

There was one questionnaire used in this study which was divided into 3 parts: screening survey, after product trial questions, and at home usage experience. This question was asked after at-home use of the product. Participants could select only one option.

How Many Packages Would You Buy?
7 days

There was one questionnaire used in this study which was divided into 3 parts: screening survey, after product trial questions, and at home usage experience.This question was asked after at-home use of the product. Participants could select only one option.

Which One Statement Best Describes How Often, if Ever, You Think You Would Buy the Spray Product in the Future?
7 days

There was one questionnaire used in this study which is divided into 3 parts: screening survey, after product trial questions, and at home usage experience. This question was asked after at-home use of the product. Participants could select only one option.

How Often do You Think This Spray Product Would Last for You Personally?
7 days

There was one questionnaire used in this study which is divided into 3 parts: screening survey, after product trial questions, and at home usage experience. This question was asked after at-home use of the product. Participants could select only one option.

Provide a Score From 1-7 to Some Statements, Depending on How Much You Think Each Statement Applies or Does Not Apply to the Spray Product That You Used
7 days

A score of 1 indicates that the statement does not apply at all to the product that you used. A score of 7 indicates that it applies completely to it. You can use any score from 1 to 7 to indicate how much or how little you think the statement applies to this product

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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Treatment GroupEXPERIMENTALParticipants will receive one dose of nasal carbon dioxide (CO2) in the study clinic under medical supervision, followed by an additional six days of at home use, up to 4 times per day.

Interventions

NameTypeDescription
Carbon DioxideDRUGNasal administration of carbon dioxide (CO2) through the delivery device for 10 seconds
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites4

Inclusion Criteria: * Participant who demonstrate understanding of, and willingness to participate in the study * Aged at least 18 years. * Understands and is willing, able and likely to comply with all study procedures and restrictions. * Good general and mental health with, in the opinion of the ...

Countries:United States
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Frequently asked questions about Carbon Dioxide

What is Carbon Dioxide used for?

Carbon Dioxide is an investigational small molecule being developed for the treatment of nasal congestion. It is administered as a nasal spray. The drug is currently in Phase 2 clinical development and is not approved for any use.

Who makes Carbon Dioxide?

Carbon Dioxide is being developed by GSK plc, a pharmaceutical company traded on the New York Stock Exchange under the ticker symbol GSK. The company is conducting clinical trials to evaluate the drug's potential in treating nasal congestion.

What phase is Carbon Dioxide in?

Carbon Dioxide is in Phase 2 clinical development. It is an investigational drug and has not been approved by regulatory authorities. One Phase 2 trial has been completed, with no active trials currently ongoing.

What clinical trials is Carbon Dioxide in?

Carbon Dioxide has one completed clinical trial, identified as NCT02113449, titled "Market Potential of Carbon Dioxide Nasal Spray." This Phase 2 study enrolled 147 participants in the United States and evaluated the drug for nasal congestion.

Is Carbon Dioxide the same as CO2?

Carbon Dioxide is the chemical compound CO2. In the context of this drug, it is being developed as a nasal spray formulation for nasal congestion. The drug is currently in Phase 2 clinical trials and is not approved.