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Avandia

Phase 3

Insulin Resistance | Small molecule | Metabolic |GSK plc|Last Updated: Dec 5, 2016

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment18

FDA Designations

No designations recorded

Clinical trial landscape

Avandia · 1 trial · 1 indication

Phase 3 1
NCT00197132Study In Patients With Insulin ResistanceInsulin Resistance
COMPLETED18 Analytics
PHASE3COMPLETED
Study In Patients With Insulin Resistance
Insulin ResistanceUnlock trial analytics

Study Endpoints

Primary Endpoints

Forearm blood flow

Secondary Endpoints

Insulin sensitivity, plasma volume, transcapillary escape rate, inhibition to vasodialtory response, changes in cardiac output, plasma catecholamine levels, changes in plasma hormone/markers of vascular permeability, safety and tolerability.
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelCROSSOVER
PurposeTREATMENT

Interventions

NameTypeDescription
AvandiaDRUG -
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Eligibility Criteria

Age Range30 Years to 65 Years
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * BMI 27-36 kg/m2 inclusive and at least two additional features of the metabolic syndrome or a first degree relative with a history of type 2 diabetes mellitus. BMI = Weight/height², (where weight is in kg, height in m). * Male or female aged 30 to 65 years, inclusive, at scree...

Countries:Netherlands
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Frequently asked questions about Avandia

What is Avandia used for in insulin resistance?

Avandia is a small molecule drug being developed for the treatment of insulin resistance, a metabolic condition. It is currently in Phase 3 clinical development and is being studied in patients with insulin resistance. The drug is intended to address this condition, though it remains investigational and has not been approved for this use.

What does Avandia target?

Avandia is a small molecule drug being developed for insulin resistance. The specific molecular target of Avandia is not disclosed in the available information. The drug is being studied in a Phase 3 clinical trial to evaluate its effects on insulin resistance, a metabolic condition.

Who makes Avandia?

Avandia is being developed by GSK plc, a pharmaceutical company listed on the stock exchange under the ticker GSK. GSK is conducting clinical research on Avandia for the treatment of insulin resistance, a metabolic condition. The drug is currently in Phase 3 development.

What phase is Avandia in?

Avandia is in Phase 3 clinical development for the treatment of insulin resistance. It is an investigational drug, meaning it has not been approved by regulatory authorities. The Phase 3 trial has been completed, and the drug is being evaluated for its safety and efficacy in patients with insulin resistance.

What clinical trials is Avandia in?

Avandia has one completed Phase 3 clinical trial with the identifier NCT00197132, titled "Study In Patients With Insulin Resistance." This trial enrolled 18 patients with insulin resistance in the Netherlands, with a minimum age of 30 years. The study was randomized, double-blind, and uncontrolled, and it has been completed.

Is Avandia the same as rosiglitazone?

Avandia is the brand name for the drug rosiglitazone, which is used to treat insulin resistance. However, the available information does not specify alternative names for Avandia. The drug is being developed by GSK plc and is currently in Phase 3 clinical trials for insulin resistance.