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AH23844

Phase 2

Gastroesophageal Reflux Disease | Small molecule | Gastrointestinal |GSK plc|Last Updated: Jan 19, 2017

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment92

FDA Designations

No designations recorded

Clinical trial landscape

AH23844 · 1 trial · 2 indications

Phase 2 1
NCT00405119A Study To Investigate The Effectiveness Of AH234844 (Lavoltidine) Compared With NEXIUM And Ranitidine.Gastroesophageal Reflux Disease
COMPLETED92 Analytics
PHASE2COMPLETED
A Study To Investigate The Effectiveness Of AH234844 (Lavoltidine) Compared With NEXIUM And Ranitidine.
Gastroesophageal Reflux DiseaseUnlock trial analytics

Study Endpoints

Primary Endpoints

pH over 24hours
over 24hours

Secondary Endpoints

%24 hours pH>4 Median gastric pH Adverse events
over 24 hours
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelCROSSOVER
PurposeDIAGNOSTIC

Interventions

NameTypeDescription
AH23844 (lavoltidine)DRUG -
NEXIUM (esomeprazole)DRUG -
ZANTAC (ranitidine)DRUG -
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Eligibility Criteria

Age Range18 Years to 55 Years
SexMALE
Healthy VolunteersYes
Study Sites2

Inclusion criteria: * Subject must have a Body Mass Index (BMI) from 19-30 kg/m2 * Subject does not present with abnormal clinical lab findings * Subject is able to tolerate a nasogastric pH electrode. Exclusion criteria: * Subject is Helicobacter-positive on a C13 urea breath test * Subject has ...

Countries:Australia
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Frequently asked questions about AH23844

What is AH23844 used for?

AH23844 is an investigational small molecule being studied for the treatment of Gastroesophageal Reflux Disease (GERD). It is currently in Phase 2 clinical development and has not been approved by regulatory authorities.

Who makes AH23844?

AH23844 is being developed by GSK plc, a pharmaceutical company listed on the stock exchange under the ticker symbol GSK. The drug is in Phase 2 clinical trials for Gastroesophageal Reflux Disease.

What phase is AH23844 in?

AH23844 is in Phase 2 clinical development. It is an investigational drug, meaning it has not yet been approved for commercial use. The drug is being studied for the treatment of Gastroesophageal Reflux Disease.

What clinical trials is AH23844 in?

AH23844 has one completed Phase 2 clinical trial with the identifier NCT00405119. This study investigated the effectiveness of AH234844 (Lavoltidine) compared with NEXIUM and ranitidine in patients with Gastroesophageal Reflux Disease. The trial enrolled 92 participants in Australia.

Is AH23844 the same as Lavoltidine?

Yes, AH23844 is also known as Lavoltidine. In clinical trial NCT00405119, the drug is referred to as AH234844 (Lavoltidine), indicating that AH23844 and Lavoltidine are alternative names for the same investigational drug.