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RIG-C

Phase 1

Rabies | Monoclonal antibody | Infectious Disease |Grifols, S.A.|Last Updated: Jul 24, 2014

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment12

FDA Designations

No designations recorded

Clinical trial landscape

RIG-C · 1 trial · 1 indication

Phase 1 1
NCT02139657An Open-label, Single-Arm Study to Evaluate the Safety and Rabies Virus Antibody Titers of Intramuscularly Administered Rabies Immune Globulin (Human)Rabies
COMPLETED12 Analytics
PHASE1COMPLETED
An Open-label, Single-Arm Study to Evaluate the Safety and Rabies Virus Antibody Titers of Intramuscularly Administered Rabies Immune Globulin (Human)
RabiesUnlock trial analytics

Study Endpoints

Primary Endpoints

Rabies Virus Antibody Titer
10 days post-RIG-C dosing

Secondary Endpoints

Number of subjects who discontinue due to adverse events
21 days
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
RIG-CEXPERIMENTALSingle 20 IU/kg dose of RIG-C by intramuscular injection

Interventions

NameTypeDescription
RIG-CBIOLOGICAL -
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Eligibility Criteria

Age Range18 Years to 65 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * In good health in the judgment of the Investigator as determined by medical history, physical examination, and screening laboratory assessments. * Female of childbearing potential must have a negative result on the screening serum pregnancy test and must agree to practice cont...

Countries:United States
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Frequently asked questions about RIG-C

What is RIG-C used for?

RIG-C is an investigational monoclonal antibody being developed for rabies. It is intended to provide rabies virus antibodies, and it is currently in Phase 1 clinical development. The drug is not yet approved and remains under study for this infectious disease indication.

Who makes RIG-C?

RIG-C is being developed by Grifols, S.A., a biopharmaceutical company traded under the ticker GRFS. The company is conducting clinical research on this investigational monoclonal antibody for rabies.

What phase is RIG-C in?

RIG-C is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. One Phase 1 trial has been completed, and the drug remains under study for rabies.

What clinical trials is RIG-C in?

RIG-C has one completed clinical trial, NCT02139657, an open-label, single-arm study evaluating the safety and rabies virus antibody titers of intramuscularly administered rabies immune globulin. The trial enrolled 12 healthy volunteers in the United States.

Is RIG-C the same as rabies immune globulin?

RIG-C is being studied as a rabies immune globulin product. The completed clinical trial NCT02139657 evaluated the safety and rabies virus antibody titers of intramuscularly administered rabies immune globulin, which is the investigational product being developed by Grifols.