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GEN1056

Phase 1

Solid Tumor, Adult | Monoclonal antibody | Oncology |Genmab A/S|Last Updated: Nov 23, 2025

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment26
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT05586321Study of Safety and Antitumor Activity of GEN1056 in Participants With Advanced Solid TumorsPHASE1 COMPLETED 26Oct 1, 2022Oct 1, 2025Nov 23, 2025 -
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Study Design & Arms
Interventions
NameTypeDescription
GEN1056BIOLOGICALGEN1056 will be administered as an intravenous (IV) infusion. The dose levels will be determined by the starting dose and the escalation steps taken in the trial in Part 1. In Part 2, the dose and schedule will be decided based on data outcome from Part 1.
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