Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Calcium per · 1 trial · 1 indication
| Arm | Type | Description |
|---|---|---|
| 1 | EXPERIMENTAL | Calcium Acetate Oral Solution 667 mg per 5 mL |
| 2 | ACTIVE_COMPARATOR | Calcium Acetate 667 mg Gelcaps |
| 3 | OTHER | Calcium Citrate 950 mg Caplets |
| Name | Type | Description |
|---|---|---|
| Calcium Acetate Oral Solution 667 mg per 5 mL | DRUG | Drug: Calcium acetate oral solution 667 mg calcium acetate, USP per 5 mL (169 mg of elemental calcium per 5 mL); Dosage: 30 mL of calcium acetate oral solution; Dosage frequency: three times per day with meals; Duration: 3 days and the morning of day 4, in total ten doses |
| Calcium Acetate 667 mg GelCaps | DRUG | Drug: PhosLo GelCaps (calcium acetate) 667 mg (169 mg of elemental calcium per gelcap); Dosage: 6 gelcaps; Dosage frequency: three times per day with meals; Duration: 3 days and the morning of day 4, in total ten doses. |
| Calcium Citrate 950 mg Caplets | DIETARY_SUPPLEMENT | Drug: Calcium Citrate 950 mg Caplets (200 mg of elemental calcium per caplet); Dosage: 5 caplets; Dosage frequency: three times per day with meals; Duration: 3 days and the morning of day 4, in total ten doses |
Inclusion Criteria: * Signed and dated informed consent form * Ages: 18-75 years * Serum Calcium level 8.6-10.2 mg/dL * 25 vitamin D level 20-100 ng/mL * 1, 25 dihydroxy vitamin D level 6-62 pg/mL * Fasting glucose level of 65-99 mg/dL (min 8 hr fast) * iPTH level of 10-65 pg/mL * Serum phosphorous...