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EQ101

Phase 2

Alopecia Areata | Small molecule | Dermatology |Equillium, Inc.|Last Updated: Apr 10, 2025

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment36

FDA Designations

No designations recorded

Clinical trial landscape

EQ101 · 1 trial · 4 indications

Phase 2 1
NCT05589610Study of EQ101 in Adult Subjects With Moderate to Severe Alopecia AreataAlopecia Areata
COMPLETED36 Analytics
PHASE2COMPLETED
Study of EQ101 in Adult Subjects With Moderate to Severe Alopecia Areata
Alopecia AreataUnlock trial analytics

Study Endpoints

Primary Endpoints

Number of Treatment Emergent Adverse Events
Week 28

Number of participants with treatment-related adverse events as assessed by the Common Terminology Criteria for Adverse Events (CTCAE)

Secondary Endpoints

The Efficacy of EQ101 in Adult Subjects With Moderate to Severe Alopecia
Week 24
To Characterize the Pharmacokinetics (PK) of EQ101
Week 24
To Characterize the Pharmacodynamics (PD) of EQ101
Week 24
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
EQ101EXPERIMENTALEQ101 weekly

Interventions

NameTypeDescription
EQ101DRUGEQ101, 2 mg/kg, once weekly dosing, for a total of 24 doses
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Eligibility Criteria

Age Range18 Years to 60 Years
SexALL
Healthy VolunteersNo
Study Sites5

Key Inclusion Criteria: 1.Subjects have AA, meeting all of the following criteria: 1. Clinical diagnosis of AA with no other aetiology of hair loss ; 2. At least 35% scalp hair loss, as defined by a SALT score ≥ 35, at Screening and Baseline. Approximately 25% of subjects with 35% to \<50% scalp h...

Countries:AustraliaNew Zealand
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Frequently asked questions about EQ101

What is EQ101 used for?

EQ101 is an investigational small molecule being studied for the treatment of moderate to severe alopecia areata, including alopecia totalis and alopecia universalis. It is in Phase 2 clinical development and is not yet approved by regulatory authorities.

Who makes EQ101?

EQ101 is being developed by Equillium, Inc., a biopharmaceutical company traded on the Nasdaq under the ticker symbol EQ. The company is conducting clinical research to evaluate the safety and efficacy of this investigational therapy.

What phase is EQ101 in?

EQ101 is in Phase 2 clinical development. A Phase 2 study of the drug in adults with moderate to severe alopecia areata has been completed. The drug remains investigational and has not been approved for commercial use.

What clinical trials is EQ101 in?

EQ101 has been studied in a Phase 2 clinical trial with the identifier NCT05589610, titled 'Study of EQ101 in Adult Subjects With Moderate to Severe Alopecia Areata.' This single-arm, uncontrolled study enrolled 36 participants in Australia and New Zealand and has been completed.

Is EQ101 the same as any other drug?

EQ101 is a distinct investigational small molecule developed by Equillium, Inc. No alternative names for this drug have been disclosed in the available clinical trial information. It is being evaluated specifically for alopecia areata and related conditions.