Recent Updates
Recently added Catalysts

DWP-450

Phase 2

Glabellar Frown Lines | Monoclonal antibody | Other |Evolus, Inc. Common Stock|Last Updated: Apr 24, 2019

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
Premium
Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
Premium
Trial Design
UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment570
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT02428608Safety Study of DWP-450 (Botulinum Toxin, Type a) to Treat Glabellar Lines - EV-006PHASE2 COMPLETED 570May 1, 2015Nov 1, 2016Apr 24, 20191 United States
Unlock Drug Trial Details
Study Endpoints
Primary Endpoints
The Safety of Repeat DWP-450 Treatments - Proportion of Subjects With at Least One Adverse Event Over 1 Year
365 days

The primary safety analysis was the calculation of the proportion of subjects with at least one adverse event that occurred from Day 0 through Day 365.

Unlock Study Endpoints
Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
Botulinum toxin, Tyoe AEXPERIMENTALDWP-450 (Botulinum toxin, Type A)
Interventions
NameTypeDescription
DWP-450 (Botulinum purified neurotoxin, Type A)BIOLOGICALBotulinum toxin, Type A
Unlock Study Design Details
Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Subjects must be an adult 18 years of age and over * Subject is able to provide informed consent and comply with study instructions * Subject has moderate-to-severe glabellar lines on maximum frown as assessed by the investigator and subject using the GLS * Subject is willing ...

Countries:United States
Unlock Eligibility Criteria