Approval Probability
TA Base Rate
Adjusted LOA
ML Risk
Amb a 1 Immunostimulatory Oligoribonucleotide Conjugate · 1 trial · 1 indication
| Arm | Type | Description |
|---|---|---|
| TOLAMBA™ | ACTIVE_COMPARATOR | - |
| Histamine | SHAM_COMPARATOR | Histamine simulates mild redness/swelling effect seen with active comparator, TOLAMBA™. Prevents study staff from easily identifying subjects who received active comparator. |
| Name | Type | Description |
|---|---|---|
| Amb a 1 Immunostimulatory Oligoribonucleotide Conjugate | BIOLOGICAL | 6 weekly subcutaneous injections (escalating doses of 3 mcg to 30 mcg) |
| Histamine | DRUG | 6 weekly subcutaneous injections (escalating doses of 0.22 mcg to 1.1 mcg) |
Inclusion Criteria: * Is willing and able to give signed informed consent, and must have provided this consent. * Has a clinical history of seasonal allergic rhinitis with seasonal nasal allergy symptoms during each of the last 2 ragweed allergy seasons. * Has documentation of a positive skin test ...