Recent Updates
Recently added Catalysts

Viaskin PT

Phase 1

Whooping Cough | Monoclonal antibody | Infectious Disease |DBV Technologies S.A.|Last Updated: Mar 2, 2020

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDDMC
Total Trials1
Total Enrollment102

FDA Designations

No designations recorded

Clinical trial landscape

Viaskin PT · 1 trial · 1 indication

Phase 1 1
NCT03035370Viaskin Pertussis Vaccine TrialWhooping Cough
COMPLETED102 Analytics
PHASE1COMPLETED
Viaskin Pertussis Vaccine Trial
Whooping CoughUnlock trial analytics

Study Endpoints

Primary Endpoints

Incidence of Treatment-Emergent Adverse Events (AE).
From Day 0 to Day 70.

* Solicited AEs occurring from the time of each application through 14 days following Viaskin PT application; * Unsolicited AEs from the time of application through 28 days following the 1st application; * Serious Adverse Events from the time of the inform consent form signature through the final study visit of subject.

Secondary Endpoints

PT-specific antibody response (anti-PT IgG antibodies and PT-specific neutralizing antibodies).
Day 14, Day 28, Day 42, Day 70.
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeOTHER

Treatment Arms

ArmTypeDescription
Viaskin PT 25 mcgEXPERIMENTALViaskin PT 25 mcg
Viaskin PT 50 mcgEXPERIMENTALViaskin PT 50 mcg
Viaskin PT PlaceboPLACEBO_COMPARATORViaskin PT Placebo

Interventions

NameTypeDescription
Viaskin PT 25 mcgBIOLOGICALTwo applications of Viaskin 25 mcg PT at a 2-week interval (D0 and D14).
Viaskin PT 50 mcgBIOLOGICALTwo applications of Viaskin 50 mcg PT at a 2-week interval (D0 and D14).
Viaskin PT PlaceboBIOLOGICALTwo applications of Viaskin PT Placebo at a 2-week interval (D0 and D14).
Boostrix™BIOLOGICALFour weeks after the second Viaskin application (at Day 42 of the study), all subjects will receive a dose of diphtheria-tetanus-pertussis vaccine (Boostrix® dTpa) to ensure the optimal recall of their immunity against pertussis.
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to 40 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Has provided written informed consent before enrollment; * Adult male or female, ages 18 to 40 years (inclusive) at the time of enrollment; * Non-pregnant, non-lactating female; * Free of clinically significant health problems, as determined by pertinent medical history and cl...

Countries:Switzerland
Unlock Eligibility Criteria

Frequently asked questions about Viaskin PT

What is Viaskin PT used for?

Viaskin PT is an investigational vaccine being developed for the prevention of whooping cough, also known as pertussis. It is currently in Phase 1 clinical development and is not yet approved for use.

Who makes Viaskin PT?

Viaskin PT is being developed by DBV Technologies S.A., a biopharmaceutical company listed on the stock exchange under the ticker symbol DBVT.

What phase is Viaskin PT in?

Viaskin PT is in Phase 1 clinical development. It is an investigational vaccine and has not been approved by regulatory authorities. A Phase 1 trial has been completed to evaluate its safety and immunogenicity.

What clinical trials is Viaskin PT in?

Viaskin PT has been studied in one completed Phase 1 clinical trial, identified as NCT03035370. This trial, titled 'Viaskin Pertussis Vaccine Trial,' enrolled 102 healthy adult volunteers in Switzerland and was randomized, double-blind, and placebo-controlled.

How does Viaskin PT work?

Viaskin PT is a monoclonal antibody-based vaccine designed to elicit an immune response against whooping cough. It is administered via a skin patch, which delivers the antigen to the immune system to stimulate protective immunity.