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autologous tumor cell vaccine

Phase 2

Brain and Central Nervous System Tumors | Monoclonal antibody | Oncology |Community Health Systems, Inc.|Last Updated: Dec 4, 2013

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment40

FDA Designations

No designations recorded

Clinical trial landscape

autologous tumor cell vaccine · 1 trial · 1 indication

Phase 2 1
NCT00003185Biological Therapy in Treating Patients With Glioblastoma MultiformeBrain and Central Nervous System Tumors
COMPLETED40 Analytics
PHASE2COMPLETED
Biological Therapy in Treating Patients With Glioblastoma Multiforme
Brain and Central Nervous System TumorsUnlock trial analytics

Study Design & Arms

PurposeTREATMENT

Interventions

NameTypeDescription
autologous tumor cell vaccineBIOLOGICAL -
sargramostimBIOLOGICAL -
tumor-draining lymph node lymphocyte therapyBIOLOGICAL -
cyclophosphamideDRUG -
conventional surgeryPROCEDURE -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

DISEASE CHARACTERISTICS: Histologically proven glioblastoma multiforme or anaplastic astrocytoma Prior surgical resection and radiotherapy completed approximately 1 month prior to study PATIENT CHARACTERISTICS: Age: Over 18 Performance status: ECOG 0-1 OR Karnofsky 70-100% Life expectancy: Not spec...

Countries:United States
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Frequently asked questions about autologous tumor cell vaccine

What is autologous tumor cell vaccine used for?

Autologous tumor cell vaccine is an investigational cancer therapy being studied for the treatment of brain and central nervous system tumors, specifically glioblastoma multiforme. It is a personalized approach that uses a patient's own tumor cells to create a vaccine intended to stimulate an immune response against the cancer.

Who is developing autologous tumor cell vaccine?

Autologous tumor cell vaccine is being developed by Community Health Systems, Inc., a company publicly traded under the ticker symbol CYH. The company is conducting clinical research to evaluate the safety and effectiveness of this investigational therapy in patients with brain and central nervous system tumors.

What phase is autologous tumor cell vaccine in?

Autologous tumor cell vaccine is currently in Phase 2 clinical development. It is an investigational agent, meaning it has not been approved by regulatory authorities and is still undergoing clinical trials to assess its potential as a treatment for brain and central nervous system tumors.

What clinical trials is autologous tumor cell vaccine in?

Autologous tumor cell vaccine has been studied in one completed clinical trial, identified as NCT00003185, titled "Biological Therapy in Treating Patients With Glioblastoma Multiforme." This Phase 2 trial enrolled 40 participants in the United States and evaluated the vaccine in patients with brain and central nervous system tumors.

Is autologous tumor cell vaccine FDA approved?

No, autologous tumor cell vaccine is not FDA approved. It is an investigational therapy currently in Phase 2 clinical development. The completed clinical trial, NCT00003185, has finished, but the therapy has not yet received regulatory approval for the treatment of brain and central nervous system tumors.