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Test culture, Control culture

Phase 3

Infertility | Unknown | Other |The Cooper Companies, Inc.|Last Updated: May 15, 2015

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDBiomarker
Total Trials1
Total Enrollment1,332

FDA Designations

No designations recorded

Clinical trial landscape

Test culture, Control culture · 1 trial · 1 indication

Phase 3 1
NCT00565747Efficacy Study of Granulocyte-macrophage Colony Stimulating Factor (GM-CSF) for Use in Human IVFInfertility
COMPLETED1,332 Analytics
PHASE3COMPLETED
Efficacy Study of Granulocyte-macrophage Colony Stimulating Factor (GM-CSF) for Use in Human IVF
InfertilityUnlock trial analytics

Study Endpoints

Primary Endpoints

Ongoing Implantation Rate Week 7
Approximately 5 weeks from oocyte pick-up (corresponding to 7 weeks from ovulation)

Defined as number of gestational sacs with fetal heart beat, shown by ultrasound in gestational week 7 in percentage of number of embryo transferred.

Secondary Endpoints

Number of Top Quality Embryos (TQE´s)
3 days from oocyte pick-up
Live Birth
Until 7 days after birth
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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Test cultureEXPERIMENTALCulture with GM-CSF
Control culturePLACEBO_COMPARATORCulture without GM-CSF

Interventions

NameTypeDescription
Test cultureDEVICEA standard culture medium with added GM-CSF (ready-to-use)
Control cultureDEVICEThe same standard culture medium, but without any additions (ready-to-use)
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Eligibility Criteria

Age Range25 Years to 39 Years
SexFEMALE
Healthy VolunteersNo
Study Sites14

Inclusion Criteria: * The couple or single woman has signed an informed consent form before any trial-related activities. * In Vitro Fertilization (IVF) or IntraCytoplasmic Sperm Injection (ICSI) treatment indicated * 25-39 years of age (both inclusive) * Regular menstrual cycle: 21-35 days (both i...

Countries:DenmarkSweden
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Frequently asked questions about Test culture, Control culture

What is Test culture, Control culture used for?

Test culture, Control culture is an investigational therapy being studied for infertility. It is being evaluated in a Phase 3 clinical trial for use in human in vitro fertilization (IVF). The study enrolled 1,332 female participants aged 25 years and older in Denmark and Sweden.

Who makes Test culture, Control culture?

Test culture, Control culture is being developed by The Cooper Companies, Inc., which trades under the ticker symbol COO. The company is conducting clinical research on this product for infertility treatment in the context of IVF procedures.

What phase is Test culture, Control culture in?

Test culture, Control culture is in Phase 3 clinical development. The Phase 3 trial, identified as NCT00565747, has been completed. The study was a randomized, double-blind, placebo-controlled trial with biomarker selection, enrolling 1,332 participants.

What clinical trials is Test culture, Control culture in?

Test culture, Control culture has one completed Phase 3 clinical trial, NCT00565747, titled 'Efficacy Study of Granulocyte-macrophage Colony Stimulating Factor (GM-CSF) for Use in Human IVF.' The trial enrolled 1,332 female participants with infertility and was conducted in Denmark and Sweden.

Is Test culture, Control culture the same as GM-CSF?

Test culture, Control culture is associated with granulocyte-macrophage colony stimulating factor (GM-CSF) in the context of the clinical trial. The Phase 3 study NCT00565747 evaluates GM-CSF for use in human IVF, and Test culture, Control culture refers to the test and control culture conditions in that study.