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Pre-radiation temozolomide.

Phase 2

High Grade Gliomas | Small molecule | Oncology |The Cooper Companies, Inc.|Last Updated: Feb 26, 2026

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment70
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT07439172Pre-Radiation Chemotherapy for Newly Diagnosed High-Grade Glioma.PHASE2 NOT YET_RECRUITING 70Mar 1, 2026Sep 1, 2029Feb 26, 2026 -
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Study Design & Arms
Interventions
NameTypeDescription
Pre-radiation temozolomide.DRUGPatients will receive 2 cycles of pre-radiation temozolomide (200mg/m\^2). Cycles are 28-days in length. Participants will take temozolomide on days 1-5 of the 28-day cycle.
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Recent Changes (Last 90 Days)
LOWMay 24, 2026NCT07439172studyFirstPostDate: changed