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Context Therapeutics Inc.

CNTX
OvervaluedPharma · Clinical
FDA catalysts, PDUFA dates & pipeline intelligence
$0.3
▼ 0 · -0.83%

Financials

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52W LOW $0.3052W HIGH $3.62
Volume
917.66 K
Value Traded
1.06 M
Short % Float
9.08%
-3.45%Week
-19.19%1 Month
-54.2%3 Month
-87.99%6 Month
-41.44%5 Year
-41.44%All Time

Cash Data

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Key Stats

Market Cap
27.47 M
EPS (TTM)
-0.50
P/E Ratio
-
Ent. Value
-15.52 M
Total Shares
91.89 M
Float Shares
76.10 M
Insiders
17.17%
Institutions
57.63%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 1a data readout
CTIM-76 (CLDN6 x CD3 TCE)
Platinum-resistant ovarian cancer (PROC)
Fast Track
Phase 1aAntibody-Drug Conjugates (ADCs)Oncology
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PoA blends historical approval base rates, trial design score and FDA review track record.

CNTX Catalyst Timeline

Dated clinical, regulatory and corporate events for Context Therapeutics Inc.

Catalyst Timeline

Dated clinical, regulatory & corporate events for Context Therapeutics Inc.

235Total events
7Upcoming
52Tier-1 (high impact)
2021 to 2027Coverage

Upcoming catalysts 2

T2Trial Initiation
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CTIM-76
T2Runway Guidance Update
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Event history 50

▲First Patient DosedCT-202Trial
First patient dosed in Phase 1 trial of CT-202
Nectin-4 expressing recurrent, unresectable or metastatic refractory/resistant urothelial, colorectal and triple-negative breast cancerssource ↗
▼Program DiscontinuationCT-95Corporate
Discontinuation of development of CT-95
●Quarterly UpdateCorporate
Second quarter 2026 financial results
●Runway Guidance UpdateCorporate
Cash runway guidance into Q4 2027
◆Trial InitiationCT-202Trial
Phase 1 clinical trial initiation for CT-202 expected in Q3 2026
solid tumorssource ↗
▲First Patient DosedCT-202Trial
First patient dosed in Phase 1 trial
urothelial, colorectal, and triple-negative breast cancerssource ↗
●IND SubmissionCT-202IND
IND submission for CT-202
solid tumorssource ↗
▲Quarterly UpdateCorporate
Added to Russell 2000 and Russell 3000 Indexes
▲Fast Track DesignationCTIM-76Designation
FDA Fast Track Designation granted for CTIM-76 in PROC
platinum-resistant ovarian cancersource ↗
▲Topline ReadoutCTIM-76Clinical Data
Positive interim efficacy and safety results from Phase 1a dose escalation
advanced solid tumors (PROC, testicular, endometrial)source ↗
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Past FDA Catalysts and PDUFA Decisions

How CNTX actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-09-30CT-95 (MSLN x CD3) Phase 1a interim results Phase 1a
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

D30 / 100
Pipeline Score
$5M
Pipeline Value
Overvalued
Valuation Signal
3
Drugs Scored
0.2x
rNPV / MCap
Top 68%
Micro Cap
(rank 448 of 658)
Percentile Rank
Context Therapeutics Inc. faces pipeline headwinds (30/100), with $260M risk-adjusted pipeline value, led by CT-202 in Triple Negative Breast Cancer (TNBC) (Phase 1).
Showing 1 of 3 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
CT-202 Small moleculeNCT07545122Triple Negative Breast Cancer (TNBC)Phase 1 RECRUITING 162Jan 1, 2030
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Clinical Trial Results

Readouts, endpoints and source filings for every CNTX program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
CTIM-76
Fast Track
platinum-resistant ovarian cancerPhase 12026-06-15overall response rate: 29%; disease control rate: 57%; CRS events: 11%Read MoreContext Therapeutics Announces Positive Interim Efficacy and Safety Results from Ongoing Phase 1 Clinical Trial for CTIM-76Read More
Scroll for more · summaries link to the source press release
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Inside Trades

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InsiderSideSharesPriceValueDate
Pasternak AndyDirectorGrant/Award 45,000 45,000 held$0.00 06/24/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Deep Track Capital, LP 0.1 % (-66.7 %) 4.11 M 7.42 M
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CNTX Institutional Ownership Trends

Options Data

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Option Chain Statistics

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Real-Time Option Chain

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Competitive positioning

How CNTX ranks across every disease it competes in

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See how CNTX ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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CNTX News

CNTX
Sep 9, 2026
CNTXPhases

Context Therapeutics Announces First Patient Dosed in Phase 1 Trial of CT-202

Context Therapeutics has announced the dosing of the first patient in its Phase 1 trial for CT-202, a bispecific antibody targeting Nectin-4. This trial aims to evaluate CT-202's safety, tolerability, and preliminary efficacy in patients with specific cancers. The company anticipates reporting initial data in late 2027.

Read more →
CNTX
Aug 5, 2026
CNTXGeneral
▼ -27.3%on this news

Context Therapeutics Reports Second Quarter 2026 Operating and Pipeline Progress

Context Therapeutics reported its Q2 2026 financial results, highlighting progress in its clinical pipeline, particularly with CTIM-76 and CT-202. The company has received Fast Track Designation for CTIM-76 and plans to initiate a Phase 1 trial for CT-202 soon. Despite a net loss, the company has sufficient cash to fund operations into late 2027.

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CNTX
Jul 10, 2026
CNTXGeneral

Context Therapeutics Announces Inducement Grant Under Nasdaq Listing Rule 5635(c)(4)

Context Therapeutics Inc. has announced the granting of a stock option award to a new employee as an inducement for employment. This award includes 146,000 shares at an exercise price of $0.70 per share, with a 10-year term and a vesting schedule over four years. The grant complies with Nasdaq Listing Rule 5635(c)(4).

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CNTX
Jul 6, 2026
CNTXGeneral
▲ +9.8%on this news

Context Therapeutics Added to Russell 2000® and Russell 3000® Indexes

Context Therapeutics Inc. has been added to the Russell 2000 and Russell 3000 Indexes, effective June 26, 2026. This inclusion reflects the company's standing in the market as a clinical-stage biopharmaceutical firm focused on T cell engaging bispecific antibodies for solid tumors. The Russell Indexes serve as benchmarks for investment strategies and highlight the company's growth potential.

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CNTX
Jun 15, 2026
CNTXPhases
▼ -51.1%on this news

Context Therapeutics Announces Positive Interim Efficacy and Safety Results from Ongoing Phase 1 Clinical Trial for CTIM-76

Context Therapeutics announced positive interim results from its Phase 1 trial of CTIM-76, a bispecific antibody for platinum-resistant ovarian cancer. The study showed a 29% overall response rate among patients, with a favorable safety profile. The drug has received FDA Fast Track Designation, and the company plans to explore a Q3W dosing schedule in future trials.

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CNTX
May 27, 2026
CNTXConferences/Events
▲ +13.3%on this news

Context Therapeutics to Present at the Jefferies Global Healthcare Conference

Context Therapeutics Inc. announced its upcoming presentation at the Jefferies Global Healthcare Conference on June 3, 2026. The company will showcase its advancements in T cell engaging bispecific antibodies for solid tumors. Additionally, Context granted stock options to a new employee, reflecting its growth strategy. However, the company acknowledges potential risks in its forward-looking statements.

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CNTX
May 18, 2026
CNTXGeneral

Context Therapeutics Enters into License Agreement Amendment with BioAtla for CT-202

Context Therapeutics has amended its license agreement with BioAtla, allowing it to buy out future milestones and royalties for the CT-202 program. In return, Context will make a total payment of $6.5 million, thereby gaining full economic rights to CT-202, an antibody targeting Nectin-4, which is implicated in various solid tumors. The Phase 1 clinical trial of CT-202 is expected to commence in the third quarter of 2026, promising potential opportunities for long-term value as the company advances its development efforts. However, there are specific risks concerning the associated adverse events with Nectin-4 targeting.

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CNTX
May 18, 2026
CNTXPhases

Context Therapeutics Enters into License Agreement Amendment with BioAtla for CT-202 Context announces buyout of CT-202 future milestones and royalties in exchange for a fully paid-up, non-terminable license

Context Therapeutics has amended its exclusive license agreement with BioAtla for CT-202, enabling it to obtain full economic rights. This move includes an upfront payment of $4.5 million, with an additional payment of $2 million due in August 2026. The company anticipates initiating a Phase 1 clinical trial for CT-202 in the third quarter of 2026. However, CT-202 is linked to potential adverse events and the company faces various operational risks moving forward.

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CNTX
May 6, 2026
CNTXPhases

Context Therapeutics Reports First Quarter 2026 Operating and Financial Results

Context Therapeutics has reported its financial results for the first quarter of 2026, highlighting a strong cash position of $54.5 million to fund operations into mid-2027. The company anticipates key clinical data from its ongoing studies, including CTIM-76 and CT-95, with updates expected later this year. Additionally, Context received FDA Fast Track Designation for CTIM-76, marking a significant milestone in treatment development for ovarian cancer. However, the company recorded a net loss of $8.7 million, which has increased compared to the same period last year, raising concerns about rising operational costs.

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CNTX
Apr 2, 2026
CNTXFDA Updates

Context Therapeutics Announces CTIM-76 Receives FDA Fast Track Designation for the Treatment of Platinum-Resistant Ovarian Cancer

Context Therapeutics has announced that its bispecific antibody CTIM-76 has received Fast Track Designation from the FDA for the treatment of platinum-resistant ovarian cancer. This designation is designed to accelerate the development and review of therapies that meet serious unmet medical needs. Context is currently conducting a Phase 1 clinical trial to evaluate the safety and efficacy of CTIM-76, with interim data anticipated in June 2026. The designation highlights the potential of CTIM-76 to significantly impact patients who have exhausted standard treatment options.

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CNTX
Mar 24, 2026
CNTXGeneral
▲ +5.3%on this news

Context Therapeutics Reports Full Year 2025 Operating and Financial Results

Context Therapeutics reported its financial results for 2025, highlighting significant advancements in its bispecific antibody pipeline. The company anticipates interim data for CTIM-76 in June 2026 and CT-95 in September 2026. With a cash balance of $66 million, Context expects to fund operations into mid-2027 and continue delivering clinical updates throughout 2026.

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CNTX
Mar 19, 2026
CNTXConferences/Events

Context Therapeutics Announces Poster Presentation at the American Association for Cancer Research (AACR) Annual Meeting 2026

Context Therapeutics Inc. announced it will be presenting a poster at the AACR Annual Meeting 2026, showcasing preclinical data for its bispecific antibody CT-202. This antibody targets Nectin-4, a protein associated with several solid tumors, and aims to enhance therapeutic efficacy in the tumor microenvironment. Scheduled for April 21, 2026, the presentation will contribute to the company's commitment to advancing novel cancer therapies. Potential risks related to CT-202 include adverse effects like neuropathy and rash.

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CNTX
Feb 9, 2026
CNTXConferences/Events

Context Therapeutics to Participate in Upcoming Investor Conferences

Context Therapeutics Inc. has announced its participation in several upcoming investor conferences, showcasing its commitment to engaging with investors. The company is focused on developing T cell engaging bispecific antibodies for solid tumors. Live webcasts of the presentations will be accessible on their website, with replays available for 90 days.

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CNTX
Jan 19, 2026
CNTXGeneral
▲ +6.9%on this news· ran to +26% by day 3

Context Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4) - January 16, 2026

Context Therapeutics has announced the granting of non-qualified stock options to two new employees as an inducement for accepting employment. The awards, totaling 120,000 shares, were granted outside of the company's long-term incentive plan in accordance with Nasdaq Listing Rule 5635(c)(4). The options have a 10-year term and vest over four years.

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CNTX
Jan 16, 2026
CNTXGeneral
▼ -5.3%on this news· ran to +18% by day 3shared move

Context Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

Context Therapeutics Inc. announced the grant of non-qualified stock options to two newly hired employees as part of its inducement offers under Nasdaq Listing Rule 5635(c)(4). A total of 120,000 shares were awarded, with exercise prices set according to recent closing prices of the company's stock. The options come with a 10-year term and a four-year vesting schedule, reinforcing the company's aim to attract and retain talent in the competitive biopharmaceutical industry.

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CNTX
Nov 7, 2025
CNTXConferences/Events

Context Therapeutics Highlights CT-95 and CT-202 Programs at 2025 SITC Annual Meeting

Context Therapeutics showcased its CT-95 and CT-202 programs at the SITC 40th Annual Meeting. CT-95 targets mesothelin, while CT-202 focuses on Nectin-4, both aiming to enhance T cell engagement against solid tumors. The company plans to provide initial Phase 1a data for CT-95 by mid-2026 and initiate a first-in-human trial for CT-202 in Q2 2026.

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CNTX
Nov 5, 2025
CNTXPhases
▼ -5.3%on this newsshared move

Context Therapeutics Reports Third Quarter 2025 Operating and Financial Results

Context Therapeutics reported promising results from its ongoing Phase 1 trials for CTIM-76 and CT-95, indicating encouraging antitumor activity. The company holds $76.9 million in cash as of September 30, 2025, which is expected to fund operations into 2027. CEO Martin Lehr expressed optimism about the future of their T cell engaging bispecific antibodies.

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CNTX
Oct 6, 2025
CNTXConferences/Events
▲ +10%on this news· ran to +27% by day 3

Context Therapeutics Announces Poster Presentations at the Society for Immunotherapy of Cancer’s (SITC) 40th Annual Meeting

Context Therapeutics Inc. has announced two poster presentations at the SITC 40th Annual Meeting, scheduled for November 7-9, 2025. The presentations will feature a Trial in Progress for the Phase 1 clinical trial of CT-95, a bispecific antibody targeting mesothelin, and preclinical data on CT-202, which targets Nectin-4. These developments highlight the company's commitment to advancing its T cell engaging bispecific antibodies for solid tumors.

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About Context Therapeutics Inc.

Philadelphia, PA 15 employees contexttherapeutics.com
Headquarters2001 MARKET STREET, PHILADELPHIA, PA, 19103
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