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Centessa Pharmaceuticals plc

CNTA
Richly ValuedPharma · Clinical
FDA catalysts, PDUFA dates & pipeline intelligence
$40.5
▲ 0 · 0%

Last traded Jun 23, 2026. This price is not current.

Financials

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52W LOW $10.9552W HIGH $40.26
Volume
11.33 M
Value Traded
33.49 M
Short % Float
1.47%
+0.38%Week
+0.56%1 Month
+59.32%3 Month
+43.35%6 Month
+96.3%5 Year
+96.3%All Time

Cash Data

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  • Burn Trend
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Key Stats

Market Cap
6.15 B
EPS (TTM)
-1.77
P/E Ratio
-
Ent. Value
5.99 B
Total Shares
154.73 M
Float Shares
109.31 M
Insiders
29.35%
Institutions
70.86%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
PDUFA
2026
Example Drug
Treatment for example condition requiring FDA review
Phase 3Small MoleculeOncology-
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

CNTA Catalyst Timeline

Dated clinical, regulatory and corporate events for Centessa Pharmaceuticals plc

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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How CNTA actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2025-12-31ORX142 Phase 1 data readout Phase 1
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

C41 / 100
Pipeline Score
$612M
Pipeline Value
Richly Valued
Valuation Signal
5
Drugs Scored
0.1x
rNPV / MCap
Centessa Pharmaceuticals plc carries a moderate pipeline score (41/100), with $993M risk-adjusted pipeline value, led by SerpinPC in Hemophilia a (Phase 1).
Showing 1 of 5 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
SerpinPC Small moleculeCompletedNCT04073498Hemophilia aPhase 1 COMPLETED 39Sep 26, 2024
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Clinical Trial Results

Readouts, endpoints and source filings for every CNTA program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
ORX750 NT1, NT2, and IHPhase 2a2025-11-05a total of 55 participants with NT1, NT2 and IH who completed dosing with ORX750 in the 2-week crossover cohortsRead MoreCentessa Pharmaceuticals Reports Financial Results for the Third Quarter of 2025 and Provides Update on Potential Best-in-Class Orexin Receptor 2 (OX2R) Agonist ProgramRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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InsiderSideSharesPriceValueDate
Medicxi Ventures Management (Jersey) Ltd10% OwnerSell -4,398,519 $0.00 06/24/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
Avoro Capital Advisors LLC 4.5 % (25 %) 454.02 M 11.43 M -21.47% ( -3.13 M)
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CNTA Institutional Ownership Trends

Options Data

Option Volume

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Today vs avg
Option Volume
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Option Chain Statistics

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Real-Time Option Chain

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Calls vs Puts by Expiry

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Competitive positioning

How CNTA ranks across every disease it competes in

Competitive Position is a premium feature
See how CNTA ranks against every competitor across each disease it develops in: phase, best drug, trials and likelihood of approval.
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CNTA News

About Centessa Pharmaceuticals plc

Cheshire, X0 129 employees centessa.com
Headquarters3RD FLOOR, ALTRINCHAM, CHESHIRE, X0, WA14 2DT
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