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CG53135-05, velafermin

Phase 2

Stomatitis | Small molecule | Gastrointestinal |Celldex Therapeutics, Inc.|Last Updated: Mar 15, 2016

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindUNCONTROLLED
Total Trials1
Total Enrollment -

FDA Designations

No designations recorded

Clinical trial landscape

CG53135-05, velafermin · 1 trial · 1 indication

Phase 2 1
NCT00104065Safety and Efficacy of CG53135-05 in the Prevention of Oral Mucositis in Patients Receiving Bone Marrow TransplantStomatitis
COMPLETED- Analytics
PHASE2COMPLETED
Safety and Efficacy of CG53135-05 in the Prevention of Oral Mucositis in Patients Receiving Bone Marrow Transplant
StomatitisUnlock trial analytics

Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposePREVENTION

Interventions

NameTypeDescription
CG53135-05, velaferminDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites9

Inclusion Criteria: * Male or female patients ages \> 18 yrs * Patients undergoing high dose chemotherapy with or without radiation therapy treatment as conditioning for autologous hematopoietic stem cell transplantation. The conditioning regimens include at least one of the following: high dose me...

Countries:United States
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Frequently asked questions about CG53135-05, velafermin

What is CG53135-05 used for?

CG53135-05, also known as velafermin, is an investigational small molecule being studied for the prevention of oral mucositis, a form of stomatitis, in patients receiving bone marrow transplant. It is in Phase 2 clinical development and is not yet approved by the FDA.

What does CG53135-05 target?

CG53135-05, or velafermin, is a small molecule being developed by Celldex Therapeutics. Its specific molecular target has not been disclosed in available information. It is being studied for its potential to prevent oral mucositis in patients undergoing bone marrow transplantation.

Who makes CG53135-05?

CG53135-05, also known as velafermin, is being developed by Celldex Therapeutics, Inc., a biopharmaceutical company traded on NASDAQ under the ticker CLDX. The company is conducting clinical research to evaluate the drug's safety and efficacy in preventing oral mucositis.

What phase is CG53135-05 in?

CG53135-05, or velafermin, is in Phase 2 clinical development. It is an investigational drug being studied for the prevention of oral mucositis in patients receiving bone marrow transplant. It has not been approved by the FDA and remains in clinical trials.

What clinical trials is CG53135-05 in?

CG53135-05, or velafermin, has one completed Phase 2 clinical trial, NCT00104065, which evaluated its safety and efficacy in preventing oral mucositis in patients receiving bone marrow transplant. The trial was conducted in the United States and enrolled adults aged 18 years and older.

Is CG53135-05 the same as velafermin?

Yes, CG53135-05 is also known as velafermin. Both names refer to the same investigational small molecule being developed by Celldex Therapeutics for the prevention of oral mucositis in patients undergoing bone marrow transplantation.