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recombinant human Angiostatin protein

Phase 2

Carcinoma, Non-Small-Cell Lung | Small molecule | Oncology |CASI Pharmaceuticals, Inc.|Last Updated: Jan 9, 2009

Success Probability

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment -

FDA Designations

No designations recorded

Clinical trial landscape

recombinant human Angiostatin protein · 1 trial · 1 indication

Phase 2 1
NCT00049790Safety and Efficacy Study of rhAngiostatin Administered in Combination With Paclitaxel and Carboplatin to Patients With Non-Small-Cell Lung CancerCarcinoma, Non-Small-Cell Lung
COMPLETED- Analytics
PHASE2COMPLETED
Safety and Efficacy Study of rhAngiostatin Administered in Combination With Paclitaxel and Carboplatin to Patients With Non-Small-Cell Lung Cancer
Carcinoma, Non-Small-Cell LungUnlock trial analytics

Study Design & Arms

PurposeTREATMENT

Interventions

NameTypeDescription
recombinant human Angiostatin proteinDRUG -
paclitaxelDRUG -
carboplatinDRUG -
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion: * Histological or cytological confirmed Stage IIIB NSCLC with malignant pleural effusions, or Stage IV NSCLC or recurrent NSCLC * No previous chemotherapy for NSCLC * Have one lesion that is bidimensionally measurable by physical exam, MRI, or CT greater than 1 cm in diameter * Specified...

Countries:United States
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Frequently asked questions about recombinant human Angiostatin protein

What is recombinant human Angiostatin protein used for?

Recombinant human Angiostatin protein is being studied for use in non-small-cell lung cancer. It is an investigational therapy that was evaluated in a Phase 2 clinical trial in combination with paclitaxel and carboplatin for patients with this condition. The trial has been completed.

What does recombinant human Angiostatin protein target?

Recombinant human Angiostatin protein targets angiogenesis, the process of new blood vessel formation that tumors rely on for growth. By inhibiting this process, the drug aims to cut off the blood supply to the tumor. It is being studied in non-small-cell lung cancer.

Who makes recombinant human Angiostatin protein?

CASI Pharmaceuticals, Inc. (NASDAQ: CASI) is developing recombinant human Angiostatin protein. The company is conducting clinical research on this investigational therapy for non-small-cell lung cancer.

What phase is recombinant human Angiostatin protein in?

Recombinant human Angiostatin protein is in Phase 2 clinical development. It has completed a Phase 2 trial in non-small-cell lung cancer. The drug is investigational and has not been approved by the FDA.

What clinical trials is recombinant human Angiostatin protein in?

Recombinant human Angiostatin protein has one completed clinical trial, NCT00049790. This Phase 2 study evaluated the safety and efficacy of rhAngiostatin administered in combination with paclitaxel and carboplatin in patients with non-small-cell lung cancer. The trial was conducted in the United States.

Is recombinant human Angiostatin protein the same as rhAngiostatin?

Yes, recombinant human Angiostatin protein is also known as rhAngiostatin. The clinical trial NCT00049790 uses the name rhAngiostatin to refer to this investigational drug being studied for non-small-cell lung cancer.