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Allogeneic Cardiosphere-Derived Cells

Phase 2

Duchenne Muscular Dystrophy | Small molecule | Neurology |Capricor Therapeutics, Inc.|Last Updated: Jan 8, 2025

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials2
Total Enrollment33

FDA Designations

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Clinical trial landscape

Allogeneic Cardiosphere-Derived Cells · 2 trials · 2 indications

Phase 2 2
NCT06304064Halt cardiomyOPathy progrEssion in Duchenne (HOPE-OLE)Duchenne Muscular Dystrophy
COMPLETED8 Analytics
NCT02485938HOPE-Duchenne (Halt cardiomyOPathy progrEssion in Duchenne)Duchenne Muscular Dystrophy
COMPLETED25 Analytics
PHASE2COMPLETED
Halt cardiomyOPathy progrEssion in Duchenne (HOPE-OLE)
Duchenne Muscular DystrophyUnlock trial analytics
PHASE2COMPLETED
HOPE-Duchenne (Halt cardiomyOPathy progrEssion in Duchenne)
Duchenne Muscular DystrophyUnlock trial analytics

Study Design & Arms

Interventions

NameTypeDescription
Allogeneic Cardiosphere-Derived Cells (CAP-1002)BIOLOGICALIntravenous infusion delivery of Allogeneic Cardiosphere-Derived Cells (CAP-1002; 75 million CDCs)
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Frequently asked questions about Allogeneic Cardiosphere-Derived Cells

What is Allogeneic Cardiosphere-Derived Cells used for in Duchenne Muscular Dystrophy?

Allogeneic Cardiosphere-Derived Cells is an investigational cell therapy being studied for Duchenne Muscular Dystrophy, a genetic disorder that causes progressive muscle weakness and heart problems. It is being evaluated for its potential to halt cardiomyopathy progression in patients with this condition.

Who makes Allogeneic Cardiosphere-Derived Cells?

Allogeneic Cardiosphere-Derived Cells is being developed by Capricor Therapeutics, Inc., a biopharmaceutical company traded on the NASDAQ under the ticker symbol CAPR. The company is conducting clinical trials to evaluate this investigational therapy for Duchenne Muscular Dystrophy.

What phase is Allogeneic Cardiosphere-Derived Cells in?

Allogeneic Cardiosphere-Derived Cells is in Phase 2 clinical development. It is an investigational therapy, meaning it has not been approved by regulatory authorities and is still being studied for safety and efficacy in patients with Duchenne Muscular Dystrophy.

What clinical trials is Allogeneic Cardiosphere-Derived Cells in?

Allogeneic Cardiosphere-Derived Cells has been studied in two completed Phase 2 trials: NCT02485938, known as HOPE-Duchenne, which enrolled 25 patients with Duchenne Muscular Dystrophy and cardiomyopathy, and NCT06304064, known as HOPE-OLE, which enrolled 8 patients with Duchenne Muscular Dystrophy.

Is Allogeneic Cardiosphere-Derived Cells the same as CAPR-1001?

Allogeneic Cardiosphere-Derived Cells is the generic name for the investigational cell therapy developed by Capricor Therapeutics. It is also known by the brand name CAP-1002, which is the specific product candidate being studied in clinical trials for Duchenne Muscular Dystrophy.