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Testosterone

Phase 3

Hypogonadism | Small molecule | Endocrine |BrainsWay Ltd.|Last Updated: Oct 5, 2017

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLED
Total Trials1
Total Enrollment149

FDA Designations

No designations recorded

Clinical trial landscape

Testosterone · 1 trial · 1 indication

Phase 3 1
NCT00522431A Study of Fortigel Testosterone Gel 2% in Males With Low TestosteroneHypogonadism
COMPLETED149 Analytics
PHASE3COMPLETED
A Study of Fortigel Testosterone Gel 2% in Males With Low Testosterone
HypogonadismUnlock trial analytics

Study Endpoints

Primary Endpoints

Percentage of Participants Meeting Serum Total Testosterone Average Concentration (Cavg) Criteria at Day 90
0, 0.5, 1, 2, 4, 6, 8, 10, 12 and 24 hours after study drug application on day 90

Percentage of participants with Cavg0-24h ≥300-≤1140 ng/dL

Secondary Endpoints

Percentage of Participants Meeting Serum Total Testosterone Maximum Concentration (Cmax) Criteria at Day 90
0, 0.5, 1, 2, 4, 6, 8, 10, 12 and 24 hours after study drug application on day 90
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1EXPERIMENTAL2% testosterone gel

Interventions

NameTypeDescription
TestosteroneDRUG2% gel
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Eligibility Criteria

Age Range18 Years to 75 Years
SexMALE
Healthy VolunteersNo

Inclusion Criteria: * Men aged 18 - 75 years with primary or secondary hypogonadism as confirmed by: * Single serum total testosterone concentration \< 250 ng/dL, or * Two consecutive serum total testosterone concentrations \< 300 ng/dL (determined at least one week apart during the screening ...

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Frequently asked questions about Testosterone

What is Testosterone used for?

Testosterone is used for the treatment of hypogonadism and male hypogonadism, conditions in which the body does not produce enough testosterone. It is being developed as a topical gel formulation for men aged 18 years and older.

Who makes Testosterone?

Testosterone is being developed by BrainsWay Ltd., a company traded under the ticker BWAY. The drug is currently in Phase 3 clinical development for the treatment of hypogonadism in men.

What phase is Testosterone in?

Testosterone is in Phase 3 clinical development. It is an investigational drug and has not been approved by the FDA. Clinical trials are ongoing to evaluate its safety and efficacy for treating hypogonadism.

What clinical trials is Testosterone in?

Testosterone has been studied in two completed Phase 3 trials. NCT00522431 enrolled 149 males with hypogonadism, and NCT01228071 enrolled 34 males with male hypogonadism in the United States. Both trials were uncontrolled and not randomized or double-blinded.

How does Testosterone work?

Testosterone is a small molecule that works by supplementing or replacing endogenous testosterone in men with hypogonadism. It is administered as a topical gel to restore testosterone levels to a normal range, addressing symptoms associated with low testosterone.