Recent Updates
Recently added Catalysts

SUN-131 1.5% TDS

Phase 2

Chalazion | Small molecule | Ophthalmology |BrainsWay Ltd.|Last Updated: Aug 11, 2017

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDBiomarker
Total Trials1
Total Enrollment60

FDA Designations

No designations recorded

Clinical trial landscape

SUN-131 1.5% TDS · 1 trial · 1 indication

Phase 2 1
NCT02338648Safety and Efficacy Study of SUN 131 TDS as Compared to Placebo TDS in Adult Patients With a ChalazionChalazion
COMPLETED60 Analytics
PHASE2COMPLETED
Safety and Efficacy Study of SUN 131 TDS as Compared to Placebo TDS in Adult Patients With a Chalazion
ChalazionUnlock trial analytics

Study Endpoints

Primary Endpoints

Complete Response
Day 23±2

Complete response is defined as the absence of any significant clinical signs of a chalazion with possible scaring or skin defects resulting from healing of the chalazion allowed.

Secondary Endpoints

Change in Chalazion Size
Study days 47 to 60
Change in Chalazion Erythema
Study days 47 to 60
Pain Associated with the Chalazion
Study days 47 to 60
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
SUN-131 1.5% TDSEXPERIMENTALSubjects will be randomly assigned to receive SUN-131 1.5% TDS for the affected eye. All patches will be worn for 16±4 hours each day for 21 days.
Placebo TDSPLACEBO_COMPARATORPlacebo Patch for Blinding Purposes

Interventions

NameTypeDescription
SUN-131 1.5% TDSDRUGActive transdermal patch
Placebo TDSDRUGPlacebo transdermal patch for blinding
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites6

Inclusion Criteria: * 18 years of age or older of either sex and any race * Chalazion with visible single granuloma in an upper or lower eyelid. If more than one eyelid is diagnosed with a chalazion, the most inflammatory chalazion shall be selected as the study eyelid. Other eyelids containing a c...

Countries:United States
Unlock Eligibility Criteria

Frequently asked questions about SUN-131 1.5% TDS

What is SUN-131 1.5% TDS used for?

SUN-131 1.5% TDS is an investigational small molecule being developed for the treatment of chalazion, a common eyelid condition. It is administered as a topical delivery system (TDS). The drug is currently in Phase 2 clinical development and has not been approved by regulatory authorities.

Who makes SUN-131 1.5% TDS?

SUN-131 1.5% TDS is being developed by BrainsWay Ltd., a company traded on the stock exchange under the ticker BWAY. The company is conducting clinical research to evaluate the safety and efficacy of this topical treatment for chalazion.

What phase is SUN-131 1.5% TDS in?

SUN-131 1.5% TDS is in Phase 2 clinical development. It is an investigational drug, meaning it has not yet been approved by the FDA or other regulatory agencies. The drug is being studied for the treatment of chalazion in adult patients.

What clinical trials is SUN-131 1.5% TDS in?

SUN-131 1.5% TDS has one completed Phase 2 clinical trial registered as NCT02338648. This randomized, double-blind, placebo-controlled study evaluated the safety and efficacy of SUN-131 TDS compared to placebo in 60 adult patients with a chalazion in the United States.

How does SUN-131 1.5% TDS work?

SUN-131 1.5% TDS is a small molecule administered topically as a delivery system. Its specific molecular target has not been disclosed in available clinical trial information. The drug is being investigated for its potential to treat chalazion, a condition involving eyelid inflammation.