Recent Updates
Recently added Catalysts

ONO-2952

Phase 1

Healthy Adult Subjects | Small molecule | Other |BrainsWay Ltd.|Last Updated: Jun 13, 2012

Success Probability

Subscribe to view

Market & Valuation

Subscribe to view

Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDBiomarker
Total Trials1
Total Enrollment48

FDA Designations

No designations recorded

Clinical trial landscape

ONO-2952 · 1 trial · 1 indication

Phase 1 1
NCT01364441Single-Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ONO-2952 in Healthy Adult SubjectsHealthy Adult Subjects
COMPLETED48 Analytics
PHASE1COMPLETED
Single-Dose Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of ONO-2952 in Healthy Adult Subjects
Healthy Adult SubjectsUnlock trial analytics

Study Endpoints

Primary Endpoints

Safety and tolerability of ONO-2952 using vital signs, ECGs, laboratory tests, physical examinations, and incidence/severity of adverse events
up to 8 days

Secondary Endpoints

Characterization of PK of ONO-2952 through measurement of drug concentration in plasma and urine sample
up to 8 days
Effect of food on ONO-2952 pharmacokinetics by comparison of PK profile between fasted and fed conditions
up to 24 days
Unlock Study Endpoints

Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
PPLACEBO_COMPARATOR -
EEXPERIMENTAL -

Interventions

NameTypeDescription
ONO-2952DRUG3 mg to 800 mg at a single dose; 10 mg and 200 mg for food effect study
PlaceboDRUGPlacebo dosed in the same manner as ONO-2952
Unlock Study Design Details

Eligibility Criteria

Age Range18 Years to 55 Years
SexALL
Healthy VolunteersYes
Study Sites1

Inclusion Criteria: * Healthy non-smoking male or female subjects (18-55 inclusive) * Body mass index (BMI) of 19-35 kg/m2 (inclusive) * For females, surgically sterilized, postmenopausal, or who are non- lactating and agree to use a double barrier method of contraception Exclusion Criteria: * Hi...

Countries:United States
Unlock Eligibility Criteria

Frequently asked questions about ONO-2952

What is ONO-2952 used for?

ONO-2952 is an investigational small molecule being studied in healthy adult subjects. It is not approved for any indication and is in early clinical development. The completed Phase 1 trial evaluated its safety, tolerability, and pharmacokinetics in healthy volunteers.

Who makes ONO-2952?

ONO-2952 is being developed by BrainsWay Ltd., a company traded under the ticker BWAY. The drug is in Phase 1 clinical development.

What phase is ONO-2952 in?

ONO-2952 is in Phase 1 clinical development. It is an investigational drug and has not been approved by regulatory authorities. One Phase 1 trial has been completed.

What clinical trials is ONO-2952 in?

ONO-2952 has one completed clinical trial, NCT01364441, a single-dose study evaluating safety, tolerability, and pharmacokinetics in healthy adult subjects. The trial enrolled 48 participants, was randomized, double-blind, and placebo-controlled, and was conducted in the United States.

Is ONO-2952 FDA approved?

ONO-2952 is not FDA approved. It is an investigational drug in Phase 1 clinical development. The completed trial was a Phase 1 study in healthy volunteers, and no approval status has been established.