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MRX-7EAT

Phase 3

Acute Tendonitis | Small molecule | Musculoskeletal |BrainsWay Ltd.|Last Updated: Jan 17, 2018

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDBiomarker
Total Trials1
Total Enrollment350

FDA Designations

No designations recorded

Clinical trial landscape

MRX-7EAT · 1 trial · 2 indications

Phase 3 1
NCT01161615MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Tendonitis and Bursitis of the ShoulderAcute Tendonitis
COMPLETED350 Analytics
PHASE3COMPLETED
MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Tendonitis and Bursitis of the Shoulder
Acute TendonitisUnlock trial analytics

Study Endpoints

Primary Endpoints

Mean of all 24 Current Pain Intensity scores collected on Days 2 through 7 on a 0-10 NPRS.
7 days
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
PlaceboPLACEBO_COMPARATORTherapy with placebo
MRX-7EATEXPERIMENTALTherapy with experimental drug

Interventions

NameTypeDescription
MRX-7EATDRUGApplication of up to two patches for up to 7 days.
PlaceboDRUGApplication of up to two patches for up to 7 days.
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Eligibility Criteria

Age Range14 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites35

Main Inclusion Criteria: * Subject is 14 years of age or older (with assent according to state law). * Females of child bearing potential must have a negative pregnancy test. * Subject has a diagnosis of acute tendonitis or bursitis of one shoulder with the onset of the current episode 5 days and ≤...

Countries:United States
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Frequently asked questions about MRX-7EAT

What is MRX-7EAT used for?

MRX-7EAT is an investigational small molecule being developed for the treatment of acute tendonitis, a musculoskeletal condition. It is formulated as a topical patch and has been studied in patients with acute tendonitis and bursitis of the shoulder. The drug is currently in Phase 3 clinical development.

Who makes MRX-7EAT?

MRX-7EAT is being developed by BrainsWay Ltd., a company traded on the stock exchange under the ticker symbol BWAY. BrainsWay is conducting clinical trials to evaluate the safety and efficacy of MRX-7EAT for the treatment of acute tendonitis.

What phase is MRX-7EAT in?

MRX-7EAT is in Phase 3 clinical development. It is an investigational drug and has not been approved by regulatory authorities. One Phase 3 trial has been completed, which studied the drug in patients with acute tendonitis and bursitis of the shoulder.

What clinical trials is MRX-7EAT in?

MRX-7EAT has been studied in one clinical trial with the identifier NCT01161615. This was a Phase 3, randomized, double-blind, placebo-controlled study titled 'MRX-7EAT Etodolac-Lidocaine Topical Patch in the Treatment of Tendonitis and Bursitis of the Shoulder.' The trial enrolled 350 participants in the United States and has been completed.

How does MRX-7EAT work?

MRX-7EAT is a topical patch that combines etodolac and lidocaine. Etodolac is a nonsteroidal anti-inflammatory drug that reduces inflammation and pain, while lidocaine is a local anesthetic that numbs the area. This combination is designed to provide targeted relief for acute tendonitis and bursitis.

Is MRX-7EAT the same as etodolac-lidocaine?

MRX-7EAT is a formulation that contains etodolac and lidocaine, as indicated by the clinical trial title. It is a topical patch that delivers these two active ingredients. The drug is being developed specifically for the treatment of acute tendonitis and bursitis of the shoulder.