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MIM-D3

Phase 2

Dry Eye | Small molecule | Ophthalmology |BrainsWay Ltd.|Last Updated: Aug 19, 2019

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment150

FDA Designations

No designations recorded

Clinical trial landscape

MIM-D3 · 1 trial · 1 indication

Phase 2 1
NCT01257607Safety and Efficacy Study of MIM-D3 Ophthalmic Solution for the Treatment of Dry EyeDry Eye
COMPLETED150 Analytics
PHASE2COMPLETED
Safety and Efficacy Study of MIM-D3 Ophthalmic Solution for the Treatment of Dry Eye
Dry EyeUnlock trial analytics

Study Endpoints

Primary Endpoints

Corneal staining
28 days

Ocular surface damage

Secondary Endpoints

Tear film break-up time
42 days
Conjunctival redness
42 days
Tear osmolarity
42 days
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Study Design & Arms

AllocationRANDOMIZED
MaskingDOUBLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
1% MIM-D3 Ophthalmic SolutionEXPERIMENTAL -
5% MIM-D3 Ophthalmic SolutionEXPERIMENTAL -
Placebo Ophthalmic SolutionPLACEBO_COMPARATOR -

Interventions

NameTypeDescription
MIM-D3 Ophthalmic SolutionDRUG28 Days, BID
Placebo Ophthalmic SolutionDRUG28 Days, BID
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: 1. Be at least 18 years of age 2. Provide written informed consent 3. Have a reported history of dry eye 4. Have a history of use or desire to use eye drops for dry eye Exclusion Criteria: 1. Be diagnosed with an ongoing ocular infection (bacterial, viral, or fungal), or activ...

Countries:United States
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Frequently asked questions about MIM-D3

What is MIM-D3 used for?

MIM-D3 is an investigational small molecule being developed for the treatment of dry eye. It is formulated as an ophthalmic solution and is currently in clinical development for this condition.

Who is developing MIM-D3?

MIM-D3 is being developed by BrainsWay Ltd. (NASDAQ: BWAY). The company is conducting clinical trials to evaluate the safety and efficacy of MIM-D3 ophthalmic solution for dry eye.

What phase is MIM-D3 in?

MIM-D3 is in Phase 2 clinical development. A Phase 2 trial has been completed, and the drug remains investigational, meaning it has not yet been approved by regulatory authorities.

What clinical trials is MIM-D3 in?

MIM-D3 has been studied in one completed Phase 2 clinical trial, NCT01257607, which evaluated the safety and efficacy of MIM-D3 ophthalmic solution for the treatment of dry eye. The trial enrolled 150 participants in the United States.

Was the MIM-D3 trial randomized and controlled?

Yes, the Phase 2 trial of MIM-D3 was randomized, double-blind, and placebo-controlled. The study enrolled 150 participants aged 18 years and older, and it was completed in the United States.