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JTM201

Phase 2

Glabellar Lines | Monoclonal antibody | Dermatology |BrainsWay Ltd.|Last Updated: Aug 29, 2025

Success Probability

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Market & Valuation

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Trial Design

RandomizedDouble-BlindPLACEBO_CONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment480

FDA Designations

No designations recorded

Clinical trial landscape

JTM201 · 1 trial · 1 indication

Phase 2 1
NCT06246552Clinical Trial to Evaluate the Safety and Efficacy of JTM201 to Treat Moderate or Severe Glabellar LinesGlabellar Lines
COMPLETED480 Analytics
PHASE2COMPLETED
Clinical Trial to Evaluate the Safety and Efficacy of JTM201 to Treat Moderate or Severe Glabellar Lines
Glabellar LinesUnlock trial analytics

Study Endpoints

Primary Endpoints

TEAE
180 days

Treatment-emergent AEs (TEAEs) from Baseline through end of followup

SAE
180 days

Serious AEs (SAEs) from the screening period through end of follow-up

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Study Design & Arms

AllocationRANDOMIZED
MaskingQUADRUPLE
ModelPARALLEL
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
JTM201EXPERIMENTALBotulinum toxin
PlaceboPLACEBO_COMPARATORPlacebo

Interventions

NameTypeDescription
JTM201BIOLOGICALJTM201 20U in 0.5mL : JTM201 will be injected via IM in 5 glabellar location 0.1mL (4U / 0.1mL) at each location
PlaceboBIOLOGICALPlacebo 20U in 0.5mL : Placebo will be injected via IM in 5 glabellar location 0.1mL (4U / 0.1mL) at each location
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites1

Inclusion Criteria: * Subjects ≥18 years of age based on the date of the written informed consent form. * Subject is able to provide written informed consent and comply with study procedures. * Subject has moderate or severe glabellar lines on maximum frown as assessed by the investigator and subje...

Countries:United States
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Frequently asked questions about JTM201

What is JTM201 used for?

JTM201 is an investigational monoclonal antibody being developed for the treatment of moderate or severe glabellar lines, the vertical wrinkles between the eyebrows. It is currently in Phase 2 clinical development and is not yet approved by regulatory authorities.

Who makes JTM201?

JTM201 is being developed by BrainsWay Ltd., a company traded on the stock exchange under the ticker BWAY. The company is conducting clinical trials to evaluate the safety and efficacy of this investigational treatment for glabellar lines.

What phase is JTM201 in?

JTM201 is in Phase 2 clinical development. A Phase 2 clinical trial has been completed to evaluate its safety and efficacy for treating moderate or severe glabellar lines. The drug is investigational and has not received regulatory approval.

What clinical trials is JTM201 in?

JTM201 has one completed Phase 2 clinical trial registered as NCT06246552, titled "Clinical Trial to Evaluate the Safety and Efficacy of JTM201 to Treat Moderate or Severe Glabellar Lines." The trial enrolled 480 participants in the United States and was randomized, double-blind, and placebo-controlled.

What does JTM201 target?

JTM201 is a monoclonal antibody, a type of biologic drug designed to bind to a specific target in the body. However, the specific molecular target of JTM201 has not been disclosed in available clinical trial information.