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Freedom SOLO Stentless Heart Valve

Phase 3

Aortic Stenosis | Unknown | Cardiovascular |BrainsWay Ltd.|Last Updated: Jan 26, 2015

Success Probability

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Market & Valuation

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Trial Design

UNCONTROLLEDDMCBiomarker
Total Trials1
Total Enrollment251

FDA Designations

No designations recorded

Clinical trial landscape

Freedom SOLO Stentless Heart Valve · 1 trial · 2 indications

Phase 3 1
NCT01115907Freedom SOLO Stentless Heart Valve StudyAortic Stenosis
COMPLETED251 Analytics
PHASE3COMPLETED
Freedom SOLO Stentless Heart Valve Study
Aortic StenosisUnlock trial analytics

Study Endpoints

Primary Endpoints

Safety will be determined by incidence rate of adverse events
1 year

The complication and survival rates for the SOLO valve are comparable to appropriate historical controls manifested as objective performance criteria (OPCs) and to that reported in the literature for other stentless bioprostheses and stented pericardial valves.

Secondary Endpoints

Efficacy will be determined by hemodynamics
1 year
Effectiveness will be determined by NYHA Classification comparisons
1 year
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Study Design & Arms

AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT

Treatment Arms

ArmTypeDescription
Freedom SOLO stentless valve implantEXPERIMENTALAppropriate subjects will receive the Freedom SOLO stentless valve implant as a replacement for a diseased or damaged native or prosthetic aortic valve.

Interventions

NameTypeDescription
Freedom SOLO Stentless Heart ValveDEVICEFreedom SOLO Stentless Heart Valve
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Eligibility Criteria

Age Range18 Years to N/A
SexALL
Healthy VolunteersNo
Study Sites15

Inclusion Criteria: * The subject is male or female 18 years old or older. * The subject or subject's legal representative is willing to sign the informed consent. * The subject which preoperative evaluation indicated the need for native or prosthetic aortic valve replacement. * Any subject amenabl...

Countries:United StatesCanada
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