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SYNERGY

Phase 3

Atherosclerotic Lesion(s) | Unknown | Other |Boston Scientific Corporation|Last Updated: Mar 16, 2016

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLEDBiomarker
Total Trials1
Total Enrollment100
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT01787799EVOLVE II QCA: A Prospective, Multicenter Trial to Assess the SYNERGY Stent System for the Treatment of Atherosclerotic Lesion(s)PHASE3 COMPLETED 100Mar 1, 2013Oct 1, 2014Mar 16, 201613 Australia, Japan +2
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Study Endpoints
Primary Endpoints
In-stent Late Loss
9 month

In-stent late loss at 9 months post-procedure as measured by quantitative coronary angiography (QCA)

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Study Design & Arms
AllocationNA
MaskingNONE
ModelSINGLE_GROUP
PurposeTREATMENT
Treatment Arms
ArmTypeDescription
SYNERGY Stent SystemEXPERIMENTALSYNERGY Everolimus-Eluting Platinum Chromium Coronary Stent System (SYNERGY Stent System)
Interventions
NameTypeDescription
SYNERGYDEVICESynergy is a device/drug combination product composed of two components, a device (coronary stent system including a chromium stent platform) and a drug product (a formulation of everolimus contained in a bioabsorbable polymer coating.
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Eligibility Criteria
Age Range18 Years — N/A
SexALL
Healthy VolunteersNo
Study Sites13

Inclusion Criteria: * Subject must be at least 18 years of age * Subject (or legal guardian) understands the trial requirements and the treatment procedures and provides written informed consent before any trial-specific tests or procedures are performed * For subjects less than 20 years of age enr...

Countries:AustraliaJapanNew ZealandSingapore
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