Financials
Cash Data
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Key Stats
Upcoming Catalysts
FDA decisions, readouts and PDUFA dates · scored by probability of approval
BMY Catalyst Timeline
Dated clinical, regulatory and corporate events for Bristol-Myers Squibb Company
Catalyst Timeline
Dated clinical, regulatory & corporate events for Bristol-Myers Squibb Company
Upcoming catalysts 2
Event history 50
Past FDA Catalysts and PDUFA Decisions
How BMY actually traded into and out of each decision
| Date | Drug | Catalyst | Stage | Reaction | Event Move % | Best Trade % |
|---|---|---|---|---|---|---|
| 2026-10-25 | Pumitamig (PD-L1 × VEGF-A bsAb) | Phase 2 data presentation | Phase 2 |
Drug Pipeline Intelligence
| Product | Revenue | Prior period | Change |
|---|---|---|---|
| Eliquis | |||
| Opdivo | |||
| Orencia | |||
| Yervoy | |||
| Reblozyl | |||
| Pomalyst/Imnovid | |||
| Revlimid | |||
| Breyanzi | |||
| Camzyos | |||
| Opdualag | |||
| Opdivo Qvantig | |||
| Zeposia |
| Drug | Indication | Phase | PTRS | rNPV | Status | Enroll | Velocity | Design | Est. Completion | ML Signal | Last Change |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Iza-bren Small moleculeNCT07100080 | Non-Small Cell Lung Cancer | Phase 3 | RECRUITING | 1,350 | Nov 15, 2030 | ||||||
| Iza-bren Small moleculeNCT06926868 | Breast Neoplasms | Phase 2 | RECRUITING | 600 | May 15, 2030 | ||||||
| Iza-bren Small moleculeNCT07106762 | Urothelial Cancer | Phase 2 | RECRUITING | 470 | Nov 18, 2033 | ||||||
| Izalontamab brengitecan Monoclonal antibodyNCT06618287 | Lung Cancer | Phase 1 | RECRUITING | 416 | Feb 26, 2031 | ||||||
| Arlocabtagene autoleucel CAR-TNCT06615479 | Relapsed or Refractory Multiple Myeloma (RRMM) | Phase 3 | RECRUITING | 440 | Jun 22, 2032 | ||||||
| Arlocabtagene autoleucel CAR-TNCT06121843 | Multiple Myeloma | Phase 2 | RECRUITING | 417 | Aug 1, 2028 | ||||||
| Pumitamig Small moleculeNCT07361510 | Non-Small Cell Lung Cancer (NSCLC) | Phase 3 | RECRUITING | 1,600 | Oct 14, 2031 | ||||||
| Pumitamig Small moleculeNCT07221149 | Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma | Phase 2 | RECRUITING | 690 | Sep 11, 2032 | ||||||
| Pumitamig Small moleculeNCT07221357 | Untreated, Unresectable, or Metastatic Colorectal Cancer | Phase 2 | RECRUITING | 990 | Mar 11, 2034 | ||||||
| Pumitamig Small moleculeNCT07871214 | Early-Stage Non-Small Cell Lung Cancer | Phase 2 | NOT YET_RECRUITING | 80 | Mar 15, 2028 | ||||||
| Pumitamig Small moleculeNCT07680764 | Locally Advanced Non-Small Cell Lung Cancer (NSCLC) | Phase 2 | RECRUITING | 160 | Sep 15, 2030 | ||||||
| Pumitamig Small moleculeNCT07291076 | Hepatocellular Carcinoma (HCC) | Phase 1 | RECRUITING | 198 | Oct 14, 2031 | ||||||
| Pumitamig Small moleculeNCT07293351 | Advanced Renal Cell Carcinoma (RCC) | Phase 1 | RECRUITING | 474 | Nov 26, 2031 | ||||||
| BMS-986489 Monoclonal antibodyNCT06646276 | Extensive-Stage Small Cell Lung Cancer | Phase 3 | RECRUITING | 530 | Jul 14, 2031 | ||||||
| Mezigdomide Small moleculeNCT05552976 | Relapsed or Refractory Multiple Myeloma | Phase 3 | ACTIVE NOT_RECRUITING | 1,416 | Jul 25, 2029 | ||||||
| Mezigdomide Small moleculeNCT03989414 | Multiple Myeloma | Phase 1 | ACTIVE NOT_RECRUITING | 746 | Nov 30, 2026 | ||||||
| Xanomeline and trospium chloride Small moleculeNCT05980949 | Psychosis Associated With Alzheimer's Disease | Phase 3 | RECRUITING | 1,910 | Sep 7, 2027 | ||||||
| Xanomeline and trospium chloride Small moleculeNCT07284745 | Irritability Associated With Autism Spectrum Disorder | Phase 3 | NOT YET_RECRUITING | 352 | Aug 6, 2029 | ||||||
| Xanomeline and trospium chloride Small moleculeNCT06951711 | Bipolar Disorder Type I With Mania or Mania With Mixed Features | Phase 3 | RECRUITING | 274 | Nov 2, 2026 | ||||||
| Xanomeline and trospium chloride Small moleculeNCT06951698 | Bipolar-I Disorder With Mania or Mania With Mixed Features | Phase 3 | RECRUITING | 274 | Nov 1, 2026 | ||||||
| Xanomeline and trospium chloride Small moleculeNCT06929273 | Bipolar Disorder Type I With Mania | Phase 3 | RECRUITING | 450 | Jun 13, 2028 | ||||||
| Xanomeline/Trospium Chloride Small moleculeNCT07140913 | Mania | Phase 3 | RECRUITING | 424 | Jun 28, 2027 | ||||||
| Xanomeline and trospium chloride Small moleculeNCT06976216 | Alzheimer Disease | Phase 3 | RECRUITING | 2,553 | Feb 23, 2029 | ||||||
| Xanomeline/Trospium Chloride Small moleculeNCT07011745 | Alzheimer Disease | Phase 3 | RECRUITING | 852 | Nov 13, 2028 | ||||||
| Navlimetostat Small moleculeNCT07492680 | Solid Tumors | Phase 2 | RECRUITING | 260 | May 20, 2032 |
Clinical Trial Results
Readouts, endpoints and source filings for every BMY program
| Drug Name | Indication | Phase | Date | Trial Results Summary | Title | Source |
|---|---|---|---|---|---|---|
| izalontamab brengitecan Breakthrough | EGFR-mutated non-small cell lung cancer | Phase 3 | 2026-10-26 | median progression free survival iza bren: 11.1 months; median progression free survival pbc: 5.7 months; hazard ratio: 0.40; confidence interval: 0.31-0.51; p value: <0.0001; confirmed objective response rate iza bren: 60.2%; confirmed objective response rate pbc: 34.5%; median duration of response iza bren: 10.4 months; median duration of response pbc: 5.7 monthsRead More | Izalontamab Brengitecan (Iza-Bren) Doubles Median Progression-Free Survival in Patients with Previously-Treated EGFR-Mutated Non-Small Cell Lung Cancer Compared to Chemotherapy in the Phase 3 PANKU-Lung01 StudyRead More |
Inside Trades
| Insider | Side | Shares | Price | Value | Date |
|---|---|---|---|---|---|
| Gallman CariOfficer (EVP, General Counsel) | Option | 4,559 18,208 held | $0.00 | 10/02/2026 |
Hedge Fund 13F Activity
Hedge Funds invested in BMY
| Fund | % of Portfolio | Current MV | Shares Owned | Activity |
|---|---|---|---|---|
| ORBIMED ADVISORS LLC | 1 % (-9.1 %) | 53.30 M | 925.00 K |
BMY Institutional Ownership Trends
BMY Short Interest
Shares sold short, counted twice a month.
Options Data
Option Volume
Option Chain Statistics
| Expiry | Call Vol | Put Vol | Vol P/C | Call OI | Put OI | OI P/C | IV Call | IV Call OI-Wtd | IV Call Vol-Wtd | IV Put | IV Put OI-Wtd | IV Put Vol-Wtd |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2026-10-30 | ||||||||||||
Real-Time Option Chain
| Calls | Strike | Puts | ||||
|---|---|---|---|---|---|---|
| Last | Vol | OI | Last | Vol | OI | |
| No data available | ||||||
Calls vs Puts by Expiry
Competitive positioning
How BMY ranks across every disease it competes in
BMY News
Izalontamab Brengitecan (Iza-Bren) Doubles Median Progression-Free Survival in Patients with Previously-Treated EGFR-Mutated Non-Small Cell Lung Cancer Compared to Chemotherapy in the Phase 3 PANKU-Lung01 Study
SystImmune and Bristol Myers Squibb announced positive results from the Phase 3 PANKU-Lung01 study of izalontamab brengitecan (Iza-bren) in patients with previously-treated EGFR-mutated non-small cell lung cancer. Iza-bren demonstrated a median progression-free survival of 11.1 months, significantly better than the 5.7 months for platinum-based chemotherapy. The drug showed a favorable safety profile with minimal adverse events.
Read more →Bristol Myers Squibb Presents Results from Phase 1 Breakfree-2 Study of Zolacabtagene Autoleucel (BMS-986353) in Patients with Highly Active Relapsing and Progressive Forms of Multiple Sclerosis at MSToronto 2026
Bristol Myers Squibb presented interim results from the Phase 1 Breakfree-2 study of zolacabtagene autoleucel (BMS-986353) for multiple sclerosis at MSToronto 2026. The study showed promising efficacy, with all patients at dose level 2 remaining off disease-modifying therapies. However, there were safety concerns, including one fatal event and a Grade 4 adverse event.
Read more →Pathos AI Announces Strategic Collaborations with Bristol Myers Squibb and Tempus AI to Advance AI-Driven Drug Development Beginning with Alzheimer’s Disease and Other Neurological Conditions
Pathos AI has announced strategic collaborations with Bristol Myers Squibb and Tempus AI to enhance AI-driven drug development for Alzheimer's and other neurological conditions. Tempus will create a comprehensive dataset from neurological patients, while BMS will leverage Pathos's AI platform to improve clinical trial designs. This partnership aims to accelerate insights into disease progression and therapy development.
Read more →Tempus Expands Strategic Collaboration with Bristol Myers Squibb
Tempus AI has entered a multi-year agreement with Bristol Myers Squibb to license oncology data through 2031. This collaboration enhances BMS's access to Tempus' Lens Platform, which utilizes AI for drug development. The partnership aims to accelerate drug discovery and improve patient outcomes in oncology.
Read more →Pathos AI Secures $237 Million in Series E Financing to Scale Agentic AI Drug Development Platform and Advance Oncology Pipeline
Pathos AI has raised $237 million in Series E financing, boosting its valuation to approximately $3 billion. The funds will enhance its AI platform, Foundry, and support the clinical development of its oncology pipeline, including the advancement of JSKN016. The company aims to improve drug development success rates through innovative AI-driven strategies.
Read more →Izalontamab Brengitecan (Iza-Bren) Reduced Risk of Disease Progression or Death by 59% versus Chemotherapy in Patients with Advanced HR+/HER2- Breast Cancer in Phase 3 PANKU-Breast01 Study
Bristol Myers Squibb and SystImmune reported positive Phase 3 PANKU-Breast01 results for izalontamab brengitecan (iza-bren). The drug reduced the risk of disease progression or death by 59% versus chemotherapy in advanced HR+/HER2- breast cancer. Median progression-free survival reached 8.2 months compared to 4.0 months for the control arm. The data will be presented at ESMO 2026 and published in The Lancet.
Read more →IHI and Bristol Myers Squibb Launch National Collaborative to Expand Access to Cancer Clinical Trials
The Institute for Healthcare Improvement and Bristol Myers Squibb launched a three-year initiative to enhance access to oncology clinical trials. The Cancer Collective Action Collaborative aims to address barriers faced by underrepresented populations, particularly in lung and breast cancer. The initiative will involve 24 teams working to improve patient engagement and trial participation.
Read more →Bristol Myers Squibb to Showcase Next-Generation Cancer Modalities and Leadership Across Solid Tumors at ESMO 2026
Bristol Myers Squibb will present significant oncology data at the ESMO 2026 Congress, including late-breaking Phase 2 and Phase 3 studies for its investigational drugs, izalontamab brengitecan and pumitamig. The presentations will cover a range of solid tumors, showcasing the company's advancements in cancer treatment and its focus on improving patient outcomes.
Read more →Bristol Myers Squibb Announces Positive Topline Results from the Interim Analysis of Phase 3 ACTION-1 for RYZ101, RayzeBio’s Radiopharmaceutical Therapy, in Patients with GEP-NETs
Bristol Myers Squibb has announced positive topline results from the interim analysis of its Phase 3 ACTION-1 trial for RYZ101, a radiopharmaceutical therapy. This trial focuses on patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs). The results indicate a promising potential for RYZ101 in treating this patient population.
Read more →Bristol Myers Squibb Announces Phase 3 ALOFT-IPF Trial Evaluating Admilparant in Adults with Idiopathic Pulmonary Fibrosis Met Primary Endpoint
Bristol Myers Squibb has announced that its Phase 3 ALOFT-IPF trial evaluating Admilparant in adults with idiopathic pulmonary fibrosis has successfully met its primary endpoint. This achievement highlights the potential of Admilparant as a treatment option for this serious condition. The results may pave the way for further developments in the management of idiopathic pulmonary fibrosis.
Read more →On the 12th Edition of Global Patient Week Bristol Myers Squibb and Saudi Schizophrenia Association 'Ehtiwaa' Collaborate to Support People Living with Schizophrenia Through the 'Small Wins' Initiative
Bristol Myers Squibb (BMS) celebrated the 12th Global Patient Week in Saudi Arabia by collaborating with the Saudi Schizophrenia Association to launch the 'Small Wins' initiative. This program aims to support individuals living with schizophrenia through personalized toolkits that promote daily engagement and emotional well-being. BMS employees actively participated in assembling these kits, reinforcing the company's commitment to patient-centered care.
Read more →Bristol Myers Squibb Announces ZENBEXUSTM (iberdomide) in Combination with Daratumumab and Dexamethasone (ZDd) Demonstrates Superior Progression-Free Survival vs. Standard of Care in Relapsed and Refractory Multiple Myeloma in Phase 3...
Bristol Myers Squibb has announced that ZENBEXUSTM (iberdomide), in combination with Daratumumab and Dexamethasone, has demonstrated superior progression-free survival compared to standard care in patients with relapsed and refractory multiple myeloma. This finding comes from a Phase 3 clinical trial, highlighting the potential of this combination therapy to improve treatment outcomes for patients.
Read more →Driving Community Health: Bristol Myers Squibb, Emirates Thalassemia Society and Dubai Science Park Host the 6th 'Help Save a Life' Blood Donation Drive
Bristol Myers Squibb, in collaboration with the Emirates Thalassemia Society and Dubai Science Park, hosted the sixth 'Help Save a Life' blood donation drive in Dubai. This initiative aims to support patients with chronic blood disorders by mobilizing community members to donate blood. The event highlights the importance of reliable blood supplies for patients' treatment and reinforces the commitment to patient care in the UAE.
Read more →Bristol Myers Squibb Deepens Commitment to Healthcare Professionals Through Champions in Care Movement
Bristol Myers Squibb has expanded its Champions in Care initiative, now in its second year, to honor healthcare professionals and support medically underserved communities. The campaign introduces a $1 million grant program for nonprofit organizations, allowing healthcare professionals to nominate groups that address community healthcare gaps. Nominations are open until November 30, 2026.
Read more →U.S. Food and Drug Administration Approves Expanded Indication for Bristol Myers Squibb’s CAMZYOS® (mavacamten) for the Treatment of Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM) in Adults and Pediatric Patients*
The U.S. FDA has approved an expanded indication for Bristol Myers Squibb's CAMZYOS (mavacamten), allowing its use in treating symptomatic obstructive hypertrophic cardiomyopathy (oHCM) in both adults and pediatric patients. This approval reflects the drug's efficacy and the company's commitment to addressing this serious condition. The expanded use is expected to enhance treatment options for patients suffering from oHCM.
Read more →Bristol Myers Squibb Announces First Presentation of Results for ZENBEXUS™ (iberdomide) in Combination with Daratumumab from Phase 3 EXCALIBER-RRMM Trial in Relapsed or Refractory Multiple Myeloma
Bristol Myers Squibb has announced the first presentation of results for ZENBEXUS™ (iberdomide) in combination with Daratumumab from the Phase 3 EXCALIBER-RRMM trial. This trial focuses on patients with relapsed or refractory multiple myeloma, showcasing the potential of this combination therapy. The announcement marks a significant step in the ongoing development of innovative treatments for this patient population.
Read more →New Member Alert: RAAP WELCOMES BRISTOL MYERS SQUIBB! BMS Joins as Newest Member of RAAP
Bristol Myers Squibb (BMS) has joined the Rare Access Action Project (RAAP) to enhance efforts in addressing access challenges for rare disease patients. BMS's participation is expected to bring valuable insights and strengthen the coalition's mission to improve patient access to innovative treatments. The collaboration aims to foster solutions that benefit patients facing serious diseases.
Read more →