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Bristol-Myers Squibb Company

BMYFDA catalysts, PDUFA dates & pipeline intelligence
$61.61
▲ +0.13 · +0.21%

Financials

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Revenue
R&D Expenses
Operating CF
Total Assets
Total Liabilities
Equity
Shares Out.
D/E Ratio
Quarterly Cash
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52W LOW $42.5252W HIGH $68.64
Volume
7.76 M
Value Traded
632.33 M
Short % Float
2.25%
Days to Cover
3.0
+4.73%Week
-3.55%1 Month
-1.52%3 Month
+6.63%6 Month
-11.57%5 Year
+2,822.58%All Time

Cash Data

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Key Stats

Market Cap
125.85 B
EPS (TTM)
4.54
P/E Ratio
13.56
Ent. Value
157.64 B
Total Shares
2.04 B
Float Shares
2.04 B
Insiders
0.32%
Institutions
85.23%

Upcoming Catalysts

FDA decisions, readouts and PDUFA dates · scored by probability of approval

Catalyst Drug / Treatment Stage Prob. of Approval Description Drug Type Therapeutic Area Source
Phase 2 data presentation
Pumitamig (PD-L1 × VEGF-A bsAb)
Unresectable neuroendocrine neoplasms, second-line pumitamig plus chemotherapy
Phase 2BiologicsOncology
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Every FDA decision, readout and PDUFA date, with drug type, therapeutic area and a PoA score you can trade on.
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PoA blends historical approval base rates, trial design score and FDA review track record.

BMY Catalyst Timeline

Dated clinical, regulatory and corporate events for Bristol-Myers Squibb Company

Catalyst Timeline

Dated clinical, regulatory & corporate events for Bristol-Myers Squibb Company

586Total events
44Upcoming
388Tier-1 (high impact)
2019 to 2031Coverage

Upcoming catalysts 2

T1Late-Breaker
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izalontamab brengitecanFiled
T3Poster Presentation
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izalontamab brengitecanFiled

Event history 50

▲Late-Breakerizalontamab brengitecanFiledPresentation
Late-breaking oral presentation of PANKU-Breast01 at ESMO 2026
HR+/HER2- breast cancersource ↗
◆Oral PresentationNivolumabApprovedPresentation
Phase 3 neoadjuvant/adjuvant nivolumab results in muscle-invasive bladder cancer at ESMO 2026
muscle-invasive bladder cancersource ↗
◆Poster PresentationPresentation
Poster on homozygous MTAP deletion in advanced solid tumors at ESMO 2026
advanced solid tumorssource ↗
▲Additional Datazolacabtagene autoleucelClinical Data
Secondary efficacy results: 60/60 DL2 patients remained off DMTs; NEDA in 6/7 haRMS
highly active relapsing multiple sclerosis and progressive forms of multiple sclerosissource ↗
▲Oral Presentationzolacabtagene autoleucelPresentation
Interim Breakfree-2 results in haRMS and PMS presented orally at MSToronto 2026
highly active relapsing multiple sclerosis and progressive forms of multiple sclerosissource ↗
●Safety Data Updatezolacabtagene autoleucelClinical Data
Interim safety data from Breakfree-2 MS cohorts: CRS in 42.4%, ICANS in 7.6%
highly active relapsing multiple sclerosis and progressive forms of multiple sclerosissource ↗
▲Oral Presentationizalontamab brengitecanFiledPresentation
Late-breaking oral presentation of PANKU-Breast01 at ESMO 2026
HR+/HER2- breast cancersource ↗
▲Topline Readoutizalontamab brengitecanFiledClinical Data
Positive interim Phase 3 PANKU-Breast01 results reported
HR+/HER2- breast cancersource ↗
▲Primary Endpoint Metizalontamab brengitecanFiledClinical Data
PANKU-Breast01 met primary PFS endpoint (HR 0.41, p<0.0001)
HR+/HER2- breast cancersource ↗
▲Publicationizalontamab brengitecanFiledPresentation
PANKU-Breast01 results published in The Lancet
HR+/HER2- breast cancersource ↗
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Every PDUFA date, readout, approval and corporate move, tiered by market impact and updated daily.
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Past FDA Catalysts and PDUFA Decisions

How BMY actually traded into and out of each decision

Date Drug Catalyst Stage Reaction Event Move % Best Trade %
2026-10-25Pumitamig (PD-L1 × VEGF-A bsAb) Phase 2 data presentation Phase 2
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Reaction: 30 trading days around the event · Event Move: close to close on decision day · Best Trade: peak run-up from entry 10 days before the decision

Drug Pipeline Intelligence

Pipeline Score
Pipeline Value
Commercial Value
Valuation Signal
92
Drugs Scored
rNPV / MCap
Top Drug
Top 1%
Large Pharma
(rank 8 of 657)
Percentile Rank
Commercial products (revenue basis: trailing 4 quarters of total revenue (10-K and 10-Q), to Jun 2026; product lines: last four quarters to Jun 2026 (10-K and 10-Q))
ProductRevenuePrior periodChange
Eliquis
Opdivo
Orencia
Yervoy
Reblozyl
Pomalyst/Imnovid
Revlimid
Breyanzi
Camzyos
Opdualag
Opdivo Qvantig
Zeposia
Top 12 of 17 product lines shown.
Showing 93 of 886 assets
DrugIndicationPhasePTRSrNPVStatusEnrollVelocityDesignEst. CompletionML SignalLast Change
Iza-bren Small moleculeNCT07100080Non-Small Cell Lung CancerPhase 3 RECRUITING 1,350Nov 15, 2030
Iza-bren Small moleculeNCT06926868Breast NeoplasmsPhase 2 RECRUITING 600May 15, 2030
Iza-bren Small moleculeNCT07106762Urothelial CancerPhase 2 RECRUITING 470Nov 18, 2033
Izalontamab brengitecan Monoclonal antibodyNCT06618287Lung CancerPhase 1 RECRUITING 416Feb 26, 2031
Arlocabtagene autoleucel CAR-TNCT06615479Relapsed or Refractory Multiple Myeloma (RRMM)Phase 3 RECRUITING 440Jun 22, 2032
Arlocabtagene autoleucel CAR-TNCT06121843Multiple MyelomaPhase 2 RECRUITING 417Aug 1, 2028
Pumitamig Small moleculeNCT07361510Non-Small Cell Lung Cancer (NSCLC)Phase 3 RECRUITING 1,600Oct 14, 2031
Pumitamig Small moleculeNCT07221149Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal AdenocarcinomaPhase 2 RECRUITING 690Sep 11, 2032
Pumitamig Small moleculeNCT07221357Untreated, Unresectable, or Metastatic Colorectal CancerPhase 2 RECRUITING 990Mar 11, 2034
Pumitamig Small moleculeNCT07871214Early-Stage Non-Small Cell Lung CancerPhase 2 NOT YET_RECRUITING 80Mar 15, 2028
Pumitamig Small moleculeNCT07680764Locally Advanced Non-Small Cell Lung Cancer (NSCLC)Phase 2 RECRUITING 160Sep 15, 2030
Pumitamig Small moleculeNCT07291076Hepatocellular Carcinoma (HCC)Phase 1 RECRUITING 198Oct 14, 2031
Pumitamig Small moleculeNCT07293351Advanced Renal Cell Carcinoma (RCC)Phase 1 RECRUITING 474Nov 26, 2031
BMS-986489 Monoclonal antibodyNCT06646276Extensive-Stage Small Cell Lung CancerPhase 3 RECRUITING 530Jul 14, 2031
Mezigdomide Small moleculeNCT05552976Relapsed or Refractory Multiple MyelomaPhase 3 ACTIVE NOT_RECRUITING 1,416Jul 25, 2029
Mezigdomide Small moleculeNCT03989414Multiple MyelomaPhase 1 ACTIVE NOT_RECRUITING 746Nov 30, 2026
Xanomeline and trospium chloride Small moleculeNCT05980949Psychosis Associated With Alzheimer's DiseasePhase 3 RECRUITING 1,910Sep 7, 2027
Xanomeline and trospium chloride Small moleculeNCT07284745Irritability Associated With Autism Spectrum DisorderPhase 3 NOT YET_RECRUITING 352Aug 6, 2029
Xanomeline and trospium chloride Small moleculeNCT06951711Bipolar Disorder Type I With Mania or Mania With Mixed FeaturesPhase 3 RECRUITING 274Nov 2, 2026
Xanomeline and trospium chloride Small moleculeNCT06951698Bipolar-I Disorder With Mania or Mania With Mixed FeaturesPhase 3 RECRUITING 274Nov 1, 2026
Xanomeline and trospium chloride Small moleculeNCT06929273Bipolar Disorder Type I With ManiaPhase 3 RECRUITING 450Jun 13, 2028
Xanomeline/Trospium Chloride Small moleculeNCT07140913ManiaPhase 3 RECRUITING 424Jun 28, 2027
Xanomeline and trospium chloride Small moleculeNCT06976216Alzheimer DiseasePhase 3 RECRUITING 2,553Feb 23, 2029
Xanomeline/Trospium Chloride Small moleculeNCT07011745Alzheimer DiseasePhase 3 RECRUITING 852Nov 13, 2028
Navlimetostat Small moleculeNCT07492680Solid TumorsPhase 2 RECRUITING 260May 20, 2032
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Clinical Trial Results

Readouts, endpoints and source filings for every BMY program

Drug Name Indication Phase Date Trial Results SummaryTitleSource
izalontamab brengitecan
Breakthrough
EGFR-mutated non-small cell lung cancerPhase 32026-10-26median progression free survival iza bren: 11.1 months; median progression free survival pbc: 5.7 months; hazard ratio: 0.40; confidence interval: 0.31-0.51; p value: <0.0001; confirmed objective response rate iza bren: 60.2%; confirmed objective response rate pbc: 34.5%; median duration of response iza bren: 10.4 months; median duration of response pbc: 5.7 monthsRead MoreIzalontamab Brengitecan (Iza-Bren) Doubles Median Progression-Free Survival in Patients with Previously-Treated EGFR-Mutated Non-Small Cell Lung Cancer Compared to Chemotherapy in the Phase 3 PANKU-Lung01 StudyRead More
Scroll for more · summaries link to the source press release
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Inside Trades

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InsiderSideSharesPriceValueDate
Gallman CariOfficer (EVP, General Counsel)Option 4,559 18,208 held$0.00 10/02/2026
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Hedge Fund 13F Activity

Fund % of Portfolio Current MV Shares Owned Activity
ORBIMED ADVISORS LLC 1 % (-9.1 %) 53.30 M 925.00 K
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Shares held by hedge funds each quarter, and who bought or sold.

BMY Institutional Ownership Trends

BMY Short Interest

Shares sold short, counted twice a month.

2.25%
Short % of Float
of tradable shares sold short
45.8M
Shares Sold Short
+9.2% vs prior count
3.0 Moderate
Days to Cover
trading days of normal volume to buy every short share back
15.2M
Avg Daily Volume
the average used for days to cover
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Two years of days to cover and shares sold short, with every count and its change.
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Options Data

Option Volume

Open Interest
Call OI
Put OI
Put-Call Ratio
OI 30-day avg
Today vs avg
Option Volume
Call Vol
Put Vol
Put-Call Ratio
Vol 30-day avg
Today vs avg

Option Chain Statistics

ExpiryCall VolPut VolVol P/CCall OIPut OIOI P/CIV CallIV Call OI-WtdIV Call Vol-WtdIV PutIV Put OI-WtdIV Put Vol-Wtd
2026-10-30
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Per-expiry call and put volume, open interest, put-call ratios and implied volatility.
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Real-Time Option Chain

CallsStrikePuts
LastVolOILastVolOI
No data available
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Calls vs Puts by Expiry

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Competitive positioning

How BMY ranks across every disease it competes in

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BMY News

BMY
Oct 26, 2026
BMYPhases
▲ +0.2%today

Izalontamab Brengitecan (Iza-Bren) Doubles Median Progression-Free Survival in Patients with Previously-Treated EGFR-Mutated Non-Small Cell Lung Cancer Compared to Chemotherapy in the Phase 3 PANKU-Lung01 Study

SystImmune and Bristol Myers Squibb announced positive results from the Phase 3 PANKU-Lung01 study of izalontamab brengitecan (Iza-bren) in patients with previously-treated EGFR-mutated non-small cell lung cancer. Iza-bren demonstrated a median progression-free survival of 11.1 months, significantly better than the 5.7 months for platinum-based chemotherapy. The drug showed a favorable safety profile with minimal adverse events.

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BMY
Oct 23, 2026
BMYPhases
▲ +0.2%today

Bristol Myers Squibb Presents Results from Phase 1 Breakfree-2 Study of Zolacabtagene Autoleucel (BMS-986353) in Patients with Highly Active Relapsing and Progressive Forms of Multiple Sclerosis at MSToronto 2026

Bristol Myers Squibb presented interim results from the Phase 1 Breakfree-2 study of zolacabtagene autoleucel (BMS-986353) for multiple sclerosis at MSToronto 2026. The study showed promising efficacy, with all patients at dose level 2 remaining off disease-modifying therapies. However, there were safety concerns, including one fatal event and a Grade 4 adverse event.

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BMY
Oct 23, 2026
BMYGeneral
▲ +0.2%today

Pathos AI Announces Strategic Collaborations with Bristol Myers Squibb and Tempus AI to Advance AI-Driven Drug Development Beginning with Alzheimer’s Disease and Other Neurological Conditions

Pathos AI has announced strategic collaborations with Bristol Myers Squibb and Tempus AI to enhance AI-driven drug development for Alzheimer's and other neurological conditions. Tempus will create a comprehensive dataset from neurological patients, while BMS will leverage Pathos's AI platform to improve clinical trial designs. This partnership aims to accelerate insights into disease progression and therapy development.

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BMY
Oct 23, 2026
BMYGeneral
▲ +0.2%today

Tempus Expands Strategic Collaboration with Bristol Myers Squibb

Tempus AI has entered a multi-year agreement with Bristol Myers Squibb to license oncology data through 2031. This collaboration enhances BMS's access to Tempus' Lens Platform, which utilizes AI for drug development. The partnership aims to accelerate drug discovery and improve patient outcomes in oncology.

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BMY
Oct 23, 2026
BMYGeneral
▲ +0.2%today

Pathos AI Secures $237 Million in Series E Financing to Scale Agentic AI Drug Development Platform and Advance Oncology Pipeline

Pathos AI has raised $237 million in Series E financing, boosting its valuation to approximately $3 billion. The funds will enhance its AI platform, Foundry, and support the clinical development of its oncology pipeline, including the advancement of JSKN016. The company aims to improve drug development success rates through innovative AI-driven strategies.

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BMY
Oct 23, 2026
BMYPhases
▲ +0.2%today

Izalontamab Brengitecan (Iza-Bren) Reduced Risk of Disease Progression or Death by 59% versus Chemotherapy in Patients with Advanced HR+/HER2- Breast Cancer in Phase 3 PANKU-Breast01 Study

Bristol Myers Squibb and SystImmune reported positive Phase 3 PANKU-Breast01 results for izalontamab brengitecan (iza-bren). The drug reduced the risk of disease progression or death by 59% versus chemotherapy in advanced HR+/HER2- breast cancer. Median progression-free survival reached 8.2 months compared to 4.0 months for the control arm. The data will be presented at ESMO 2026 and published in The Lancet.

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BMY
Oct 22, 2026
BMYGeneral

IHI and Bristol Myers Squibb Launch National Collaborative to Expand Access to Cancer Clinical Trials

The Institute for Healthcare Improvement and Bristol Myers Squibb launched a three-year initiative to enhance access to oncology clinical trials. The Cancer Collective Action Collaborative aims to address barriers faced by underrepresented populations, particularly in lung and breast cancer. The initiative will involve 24 teams working to improve patient engagement and trial participation.

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BMY
Oct 19, 2026
BMYConferences/Events

Bristol Myers Squibb to Showcase Next-Generation Cancer Modalities and Leadership Across Solid Tumors at ESMO 2026

Bristol Myers Squibb will present significant oncology data at the ESMO 2026 Congress, including late-breaking Phase 2 and Phase 3 studies for its investigational drugs, izalontamab brengitecan and pumitamig. The presentations will cover a range of solid tumors, showcasing the company's advancements in cancer treatment and its focus on improving patient outcomes.

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BMY
Oct 12, 2026
BMYPhases

Bristol Myers Squibb Announces Positive Topline Results from the Interim Analysis of Phase 3 ACTION-1 for RYZ101, RayzeBio’s Radiopharmaceutical Therapy, in Patients with GEP-NETs

Bristol Myers Squibb has announced positive topline results from the interim analysis of its Phase 3 ACTION-1 trial for RYZ101, a radiopharmaceutical therapy. This trial focuses on patients with gastroenteropancreatic neuroendocrine tumors (GEP-NETs). The results indicate a promising potential for RYZ101 in treating this patient population.

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BMY
Oct 12, 2026
BMYPhases

Bristol Myers Squibb Announces Phase 3 ALOFT-IPF Trial Evaluating Admilparant in Adults with Idiopathic Pulmonary Fibrosis Met Primary Endpoint

Bristol Myers Squibb has announced that its Phase 3 ALOFT-IPF trial evaluating Admilparant in adults with idiopathic pulmonary fibrosis has successfully met its primary endpoint. This achievement highlights the potential of Admilparant as a treatment option for this serious condition. The results may pave the way for further developments in the management of idiopathic pulmonary fibrosis.

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BMY
Oct 12, 2026
BMYGeneral

On the 12th Edition of Global Patient Week Bristol Myers Squibb and Saudi Schizophrenia Association 'Ehtiwaa' Collaborate to Support People Living with Schizophrenia Through the 'Small Wins' Initiative

Bristol Myers Squibb (BMS) celebrated the 12th Global Patient Week in Saudi Arabia by collaborating with the Saudi Schizophrenia Association to launch the 'Small Wins' initiative. This program aims to support individuals living with schizophrenia through personalized toolkits that promote daily engagement and emotional well-being. BMS employees actively participated in assembling these kits, reinforcing the company's commitment to patient-centered care.

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BMY
Oct 8, 2026
BMYPhases

Bristol Myers Squibb Announces ZENBEXUSTM (iberdomide) in Combination with Daratumumab and Dexamethasone (ZDd) Demonstrates Superior Progression-Free Survival vs. Standard of Care in Relapsed and Refractory Multiple Myeloma in Phase 3...

Bristol Myers Squibb has announced that ZENBEXUSTM (iberdomide), in combination with Daratumumab and Dexamethasone, has demonstrated superior progression-free survival compared to standard care in patients with relapsed and refractory multiple myeloma. This finding comes from a Phase 3 clinical trial, highlighting the potential of this combination therapy to improve treatment outcomes for patients.

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BMY
Oct 5, 2026
BMYGeneral

Driving Community Health: Bristol Myers Squibb, Emirates Thalassemia Society and Dubai Science Park Host the 6th 'Help Save a Life' Blood Donation Drive

Bristol Myers Squibb, in collaboration with the Emirates Thalassemia Society and Dubai Science Park, hosted the sixth 'Help Save a Life' blood donation drive in Dubai. This initiative aims to support patients with chronic blood disorders by mobilizing community members to donate blood. The event highlights the importance of reliable blood supplies for patients' treatment and reinforces the commitment to patient care in the UAE.

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BMY
Oct 5, 2026
BMYGeneral

Bristol Myers Squibb Deepens Commitment to Healthcare Professionals Through Champions in Care Movement

Bristol Myers Squibb has expanded its Champions in Care initiative, now in its second year, to honor healthcare professionals and support medically underserved communities. The campaign introduces a $1 million grant program for nonprofit organizations, allowing healthcare professionals to nominate groups that address community healthcare gaps. Nominations are open until November 30, 2026.

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BMY
Sep 30, 2026
BMYFDA Updates

U.S. Food and Drug Administration Approves Expanded Indication for Bristol Myers Squibb’s CAMZYOS® (mavacamten) for the Treatment of Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM) in Adults and Pediatric Patients*

The U.S. FDA has approved an expanded indication for Bristol Myers Squibb's CAMZYOS (mavacamten), allowing its use in treating symptomatic obstructive hypertrophic cardiomyopathy (oHCM) in both adults and pediatric patients. This approval reflects the drug's efficacy and the company's commitment to addressing this serious condition. The expanded use is expected to enhance treatment options for patients suffering from oHCM.

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BMY
Sep 25, 2026
BMYPhases

Bristol Myers Squibb Announces First Presentation of Results for ZENBEXUS™ (iberdomide) in Combination with Daratumumab from Phase 3 EXCALIBER-RRMM Trial in Relapsed or Refractory Multiple Myeloma

Bristol Myers Squibb has announced the first presentation of results for ZENBEXUS™ (iberdomide) in combination with Daratumumab from the Phase 3 EXCALIBER-RRMM trial. This trial focuses on patients with relapsed or refractory multiple myeloma, showcasing the potential of this combination therapy. The announcement marks a significant step in the ongoing development of innovative treatments for this patient population.

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BMY
Sep 23, 2026
BMYGeneral

New Member Alert: RAAP WELCOMES BRISTOL MYERS SQUIBB! BMS Joins as Newest Member of RAAP

Bristol Myers Squibb (BMS) has joined the Rare Access Action Project (RAAP) to enhance efforts in addressing access challenges for rare disease patients. BMS's participation is expected to bring valuable insights and strengthen the coalition's mission to improve patient access to innovative treatments. The collaboration aims to foster solutions that benefit patients facing serious diseases.

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About Bristol-Myers Squibb Company

Princeton, NJ 32,500 employees bms.com
HeadquartersROUTE 206 AND PROVINCE LINE ROAD, PRINCETON, NJ, 08543
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