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RYZ101

Phase 3

GEP-NET | Small molecule | Oncology |Bristol-Myers Squibb Company|Last Updated: Jan 19, 2026

Success Probability
Approval Probability 71%
TA Base Rate26%
Adjusted LOA41%
ML RiskLOW_RISK
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Market & Valuation
rNPV $3.2B
Market Size $9.4B
Revenue Basis $1.6B
Competitors 6
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Trial Design
UNCONTROLLED
Total Trials1
Total Enrollment288
FDA Designations
No designations recorded
Clinical Trials (1)
NCT IDTitlePhaseStatusEnrollmentVelocityDesignStartCompletionLast UpdatedSitesCountries
NCT05477576Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA TherapyPHASE3 RECRUITING 288Mar 1, 2022Jul 1, 2028Jan 19, 2026 -
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Study Design & Arms
Interventions
NameTypeDescription
RYZ101DRUGRP3D as determined in Phase 1b
EverolimusDRUGEverolimus
SunitinibDRUGSunitinib
OctreotideDRUGHigh-dose octreotide
LanreotideDRUGLanreotide
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Recent Changes (Last 90 Days)
LOWMay 24, 2026NCT05477576studyFirstPostDate: changed